T
Tilman B. Drüeke
Researcher at French Institute of Health and Medical Research
Publications - 415
Citations - 22817
Tilman B. Drüeke is an academic researcher from French Institute of Health and Medical Research. The author has contributed to research in topics: Kidney disease & Hyperparathyroidism. The author has an hindex of 68, co-authored 413 publications receiving 21471 citations. Previous affiliations of Tilman B. Drüeke include Versailles Saint-Quentin-en-Yvelines University & University of Paris-Sud.
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Journal ArticleDOI
Effects of oral vitamin C supplementation in hemodialysis patients: A proteomic assessment
Eva M. Weissinger,Thao Nguyen-Khoa,Christine Fumeron,Claudine Saltiel,Michael Walden,Thorsten Kaiser,Harald Mischak,Tilman B. Drüeke,Bernard Lacour,Ziad A. Massy +9 more
TL;DR: Plasma samples from a prospective, randomized, open‐labeled trial to assess the effects of oral vitamin C supplementation reveal that more than 30 polypeptides show significant changes in the dialysis patients in comparison to controls with normal renal function, and that several polypeptide are affected/normalized by oral vitamin'C supplementation.
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Caspase-dependent apoptosis in THP-1 cells exposed to oxidized low-density lipoproteins.
Stéphanie Vicca,Carole Hennequin,Thao Nguyen-Khoa,Ziad A. Massy,Béatrice Descamps-Latscha,Tilman B. Drüeke,Bernard Lacour +6 more
TL;DR: HCl-oxLDL are as potent as Cu-ox LDL to induce high rates of apoptosis in monocytes through a caspase-dependent pathway and the resistance of differentiated THP-1 cells to oxLDL-induced apoptosis is compatible with the hypothesis that mature macrophages have prolonged survival and thereby enhance the atherogenic process.
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Respective role of uraemic toxins and myeloperoxidase in the uraemic state
Chantal Capeillère-Blandin,Valérie Gausson,Anh Thu Nguyen,Béatrice Descamps-Latscha,Tilman B. Drüeke,Véronique Witko-Sarsat +5 more
TL;DR: The observed mechanisms leading to the generation of AOPP during the course of chronic kidney disease including end-stage renal disease are suggested to be MPO-independent oxidation mechanisms.
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Effects of Silicon, Citrate and the Fasting State on the Intestinal Absorption of Aluminium in Rats
Tilman B. Drüeke,Philippe Jouhanneau,Hélène Banide,Bernard Lacour,Françoise Yiou,Grant M. Raisbeck +5 more
TL;DR: The provision of large amounts of Si in the drinking water failed to modify physiological intestinal Al absorption under basal conditions or after its stimulation by citrate, however, a prolonged fast greatly enhanced Al absorption, compared with the non-fasted state.
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Review on uraemic solutes II—Variability in reported concentrations: causes and consequences
Raymond Vanholder,Nathalie Meert,Eva Schepers,Griet Glorieux,Àngel Argilés,Philippe Brunet,Gerald M. Cohen,Tilman B. Drüeke,Harald Mischak,Goce Spasovski,Ziad A. Massy,Joachim Jankowski +11 more
TL;DR: In this paper, the authors initiated a constructive discussion about deviations in measured concentrations of uraemic solutes; these deviations, if not perceived or handled appropriately, may lead to incorrect interpretations of the pathophysiological role of URSA and/or to erroneous therapeutic decisions.