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Tilman B. Drüeke

Researcher at French Institute of Health and Medical Research

Publications -  415
Citations -  22817

Tilman B. Drüeke is an academic researcher from French Institute of Health and Medical Research. The author has contributed to research in topics: Kidney disease & Hyperparathyroidism. The author has an hindex of 68, co-authored 413 publications receiving 21471 citations. Previous affiliations of Tilman B. Drüeke include Versailles Saint-Quentin-en-Yvelines University & University of Paris-Sud.

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Effects of oral vitamin C supplementation on oxidative stress and inflammation status in haemodialysis patients

TL;DR: Short-term oral vitamin C supplementation did not modify well-defined oxidative/antioxidative stress and inflammation markers in HD patients, and whether a higher oral dose or the intravenous route can modify these markers remains to be determined.
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Direct, acute effects of Klotho and FGF23 on vascular smooth muscle and endothelium.

TL;DR: Klotho mitigates the effects of phosphate and FGF23 on contractility via increased NO production, thereby protecting the vessel to some extent against potentially noxious effects of high phosphate or F GF23 concentrations.
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Anemia and Secondary Hyperparathyroidism

TL;DR: Investigation of the influence of subtotal parathyroidectomy on the severity of the anemia of 18 uremic subjects undergoing long-term hemodialysis therapy found a significant increase of mean hematocrit value, RBC count, and hemoglobin level.
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In vivo T cell preactivation in chronic uremic hemodialyzed and non-hemodialyzed patients.

TL;DR: A similar pattern of T cell abnormalities was observed in the uremic non-hemodialyzed patients studied, and a significantly decreased IL-2 activity was detected in the supernatants of stimulated T cells from hemodialyzing patients.
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Serum erythropoietin and erythropoiesis in primary and secondary hyperparathyroidism: effect of parathyroidectomy.

TL;DR: Investigation of possible effects of PTx on serum immunoreactive erythropoietin (iEPO) in secondary and primary hyperparathyroidism patients, and in 3 patients undergoing cervicotomy for thyroid mass removal, concluded that PTx led to a striking increase of serum iEPO and blood reticulocytes in uremic patients with secondary hyperparathiroidism.