T
Tilman B. Drüeke
Researcher at French Institute of Health and Medical Research
Publications - 415
Citations - 22817
Tilman B. Drüeke is an academic researcher from French Institute of Health and Medical Research. The author has contributed to research in topics: Kidney disease & Hyperparathyroidism. The author has an hindex of 68, co-authored 413 publications receiving 21471 citations. Previous affiliations of Tilman B. Drüeke include Versailles Saint-Quentin-en-Yvelines University & University of Paris-Sud.
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Journal ArticleDOI
Restoring glutathione as a therapeutic strategy in chronic kidney disease
TL;DR: Treatment of IgA nephropathy with ACE inhibitors with cyclophosphamide, dipyridamole and warfarin with effects of triple therapy on the progression of mesangial proliferative glomerulonephritis: a two-year prospective trial.
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Clonal Chromosomal Defects in the Molecular Pathogenesis of Refractory Hyperparathyroidism of Uremia
Yasuo Imanishi,Hideki Tahara,Nallasivam Palanisamy,Sarah Spitalny,Isidro B. Salusky,William G. Goodman,Maria Luisa Brandi,Tilman B. Drüeke,Emile Sarfati,Pablo Ureña,R. S. K. Chaganti,Andrew Arnold +11 more
TL;DR: In this paper, comparative genomic hybridization (CGH) and genome-wide molecular allelotyping were performed with a large group of uremia-associated parathyroid tumors.
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Apoptosis in parathyroid hyperplasia of patients with primary or secondary uremic hyperparathyroidism
Ping Zhang,Patricia Duchambon,Jean Gogusev,Bernadette Nabarra,Emile Sarfati,Agnès Bourdeau,Tilman B. Drüeke +6 more
TL;DR: It is suggested that hyperparathyroidism is associated with a compensatory increase in apoptosis, possibly favored by a diminished Bcl-2/Bax ratio.
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Vitamin D receptor as a candidate tumor-suppressor gene in severe hyperparathyroidism of uremia.
Suzanne B. Brown,Tamika T. Brierley,Nallasivam Palanisamy,Isidro B. Salusky,William G. Goodman,Maria Luisa Brandi,Tilman B. Drüeke,Emile Sarfati,Pablo Ureña,R. S. K. Chaganti,J. Wesley Pike,Andrew Arnold +11 more
TL;DR: Observations suggest that inactivating defects within the VDR gene do not commonly contribute to the primary pathogenesis of severe refractory hyperparathyroidism in uremia.
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Critical evaluation of plasma and LDL oxidant-trapping potential in hemodialysis patients
Thao Nguyen-Khoa,Ziad A. Massy,Véronique Witko-Sarsat,Marc Thevenin,Malik Touam,Guy Lambrey,Bernard Lacour,Tilman B. Drüeke,Béatrice Descamps-Latscha +8 more
TL;DR: This study demonstrates that TRAP is not a relevant parameter for evaluating plasma or LDL antioxidant capacity in HD patients, due to the high plasma levels of uric acid, triglycerides and AOPP, which by themselves do not exert efficient antioxidant activity in vivo, but in vitro are able to scavenge the peroxyl radicals involved in the TRAP assay.