T
Tilman B. Drüeke
Researcher at French Institute of Health and Medical Research
Publications - 415
Citations - 22817
Tilman B. Drüeke is an academic researcher from French Institute of Health and Medical Research. The author has contributed to research in topics: Kidney disease & Hyperparathyroidism. The author has an hindex of 68, co-authored 413 publications receiving 21471 citations. Previous affiliations of Tilman B. Drüeke include Versailles Saint-Quentin-en-Yvelines University & University of Paris-Sud.
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Journal ArticleDOI
Apoptotic pathways involved in U937 cells exposed to LDL oxidized by hypochlorous acid.
Stéphanie Vicca,Ziad A. Massy,Carole Hennequin,Djamel Rihane,Tilman B. Drüeke,Bernard Lacour +5 more
TL;DR: The mechanism of HOCl-oxLDL-induced apoptosis in monocytic U937 cells involves the two pathways of apical caspase activation: (i) death receptor-mediated caspue-8 and (ii) mitochondria-mediatedcaspase-9, which converges in the activation of executing caspases, including casp enzyme-3, and apoptosis.
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The Role of EUTox in Uremic Toxin Research
Raymond Vanholder,Omar Abou-Deif,A. Argiles,Ulrich Baurmeister,Joachim Beige,Peter Brouckaert,Philippe Brunet,Gerald Cohen,Peter Paul De Deyn,Tilman B. Drüeke,Danilo Fliser,Griet Glorieux,Stefan Herget-Rosenthal,Walter H. Hörl,Joachim Jankowski,Achim Jörres,Ziad A. Massy,Harald Mischak,Alessandra F. Perna,Juan Mariano Rodriguez-Portillo,Goce Spasovski,Bernd Stegmayr,Peter Stenvinkel,Paul J. Thornalley,Christoph Wanner,Andrzej Wiecek +25 more
TL;DR: The activities of the European Uremic Toxin Work Group (EUTox) in the field of uremic toxin research is reviewed, which focuses essentially on questions related to solute retention and removal during chronic kidney disease, and on the deleterious impact of those solutes on biological/biochemical systems.
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Reoperation for secondary uremic hyperparathyroidism: are technical difficulties influenced by initial surgical procedure?
Pierre Cattan,Bruno Halimi,Karen Aïdan,Claire Billotey,Carmen Tamas,Tilman B. Drüeke,Emile Sarfati +6 more
TL;DR: Subtotal parathyroidectomy provides the best conditions for successful reoperation in case of recurrent hyperparathyroidism and should become the surgical treatment of choice for secondary hyperparathiroidism.
Hyperparathyroidism in Chronic Kidney Disease
TL;DR: In initial CKD stagesskeletal resistance to the action of PTH may explain why low bone turnover predominates in a significant proportion of patients, together with other conditions inhibiting bone turnover such as reduced calcitriol levels, sex hormone deficiency, diabetes, and uremic toxins.
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Rapid stimulation of calcium uptake by isolated rat enterocytes by 1,25(OH)2D3.
TL;DR: The study suggests that the early action of 1,25(OH)2D3 on the influx process of intestinal calcium transport may involve a different molecular specificity from that involved in the genomic action of 3,000-day-old rats and that changes in polyamine metabolism may play a part in this process.