T
Timothy L. Ratliff
Researcher at Purdue University
Publications - 312
Citations - 20541
Timothy L. Ratliff is an academic researcher from Purdue University. The author has contributed to research in topics: Prostate cancer & Cancer. The author has an hindex of 69, co-authored 306 publications receiving 19092 citations. Previous affiliations of Timothy L. Ratliff include University of Iowa Hospitals and Clinics & Beth Israel Deaconess Medical Center.
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Journal ArticleDOI
The etiology of interstitial cystitis.
TL;DR: The cause of interstitial cystitis remains unknown and several animal models have been described that may provide a basis for fundamental biologic studies that may aid in answering this important question.
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Prostate inflammation and its potential impact on prostate cancer: a current review.
TL;DR: The data demonstrating a correlation between inflammation and prostate cancer is reviewed as well as what is currently known about the inflammatory response in the prostate and the impact this inflammation has on the prostate tissue.
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Pten is necessary for the quiescence and maintenance of adult muscle stem cells.
Feng Yue,Pengpeng Bi,Chao Wang,Tizhong Shan,Yaohui Nie,Timothy L. Ratliff,Timothy P. Gavin,Shihuan Kuang +7 more
TL;DR: A critical function of Pten is delineated in maintaining SC quiescence and an interaction between Pten and Notch signalling is revealed and constitutive activation of Notch1 prevents SC depletion despite Pten deletion.
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Role of a bacillus Calmette-Guérin fibronectin attachment protein in BCG-induced antitumor activity.
Weicheng Zhao,Jeffrey S. Schorey,Malgorzata Bong-Mastek,Julie Ritchey,Eric J. Brown,Timothy L. Ratliff +5 more
TL;DR: Cl cloning of the M. bovis BCG FAP (FAP‐B) is reported and an important role for FAP is demonstrated in the in vivo attachment of BCG to the bladder wall and in the induction ofBCG‐mediated antitumor activity.
Journal Article
Reduction of Bladder Tumor Growth in Mice Treated with Intravesical Bacillus Calmette-Guérin and Its Correlation with Bacillus Calmette-Guérin Viability and Natural Killer Cell Activity
TL;DR: The results suggest that the therapeutic effects of BCG therapy in this murine model correlate with augmentation of NK activity and positive footpad reactions to PPD and further suggest thatThe viability and growth rate ofBCG organisms are important factors in determining the efficacy of intravesicalBCG therapy.