T
Timothy L. Ratliff
Researcher at Purdue University
Publications - 312
Citations - 20541
Timothy L. Ratliff is an academic researcher from Purdue University. The author has contributed to research in topics: Prostate cancer & Cancer. The author has an hindex of 69, co-authored 306 publications receiving 19092 citations. Previous affiliations of Timothy L. Ratliff include University of Iowa Hospitals and Clinics & Beth Israel Deaconess Medical Center.
Papers
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Journal Article
Phase I study of Ad5-TRAIL in men with clinically organ confined prostate cancer
Thomas S. Griffith,Badrinath R. Konety,Fadi N. Joudi,Howard A. Aubert,Michael B. Cohen,Timothy L. Ratliff,Richard D. Williams +6 more
TL;DR: The primary objective of the study is to determine the local and systemic toxicity associated with intraprostatic injection of Ad5-TRAIL delivered in a collagen matrix in men with locally confined prostate cancer, and determine the maximum tolerated dose from four different dose levels.
Book ChapterDOI
Interferon as an Antitumor Agent for Urologic Tumors
TL;DR: In recent years there has been considerable interest in interferon (IFN) as a possible antitumor agent but a clear definition of the usefulness of IFN as an antitumors agent remains elusive.
Journal ArticleDOI
Biomarker distribution after injection into the canine prostate: implications for gene therapy.
D.R. Siemens,T. Iwasawa,J. C. Austin,Richard D. Williams,William A. See,Sean P. Hedican,James Tartaglia,C.M. Flynn,Michael B. Cohen,J. Rodgers,Timothy L. Ratliff +10 more
TL;DR: The distribution of biomarkers after transrectal injection into the canine prostate is evaluated and a method for enhancing the distribution of gene expression is reported.
Journal ArticleDOI
Inhibition of mouse bladder tumor proliferation by alpha difluoromethylornithine and interferon in vitro and in vivo.
TL;DR: DFMO inhibits proliferation of MBT-2 cells in vitro and exhibits a similar effect in vivo against subcutaneous and intravesical tumor implants and the combination of DFMO and IFN alpha, beta exhibited enhanced activity in vitro, but no enhancement was observed with combination therapy in vivo.
Journal ArticleDOI
Early microrecanalization of vas deferens following biodegradable graft implantation in bilaterally vasectomized rats.
Christopher M. Simons,Barry R. De Young,Thomas S. Griffith,Timothy L. Ratliff,Erin N. Boote Jones,Surya K. Mallapragada,Moshe Wald +6 more
TL;DR: In this article, a biodegradable graft for reconstruction of rat vasa deferentia with long obstructed or missing segments was used to allow passage of sperm in Sprague-Dawley rats.