T
Timothy L. Ratliff
Researcher at Purdue University
Publications - 312
Citations - 20541
Timothy L. Ratliff is an academic researcher from Purdue University. The author has contributed to research in topics: Prostate cancer & Cancer. The author has an hindex of 69, co-authored 306 publications receiving 19092 citations. Previous affiliations of Timothy L. Ratliff include University of Iowa Hospitals and Clinics & Beth Israel Deaconess Medical Center.
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Journal ArticleDOI
Intravesical chemotherapy and immunotherapy: how do we assess their effectiveness and what are their limitations and uses?
Donald L. Lamm,Apm van der Meijden,Hideyuki Akaza,ChB Brendler,PO Hedlund,Y Mizutani,Timothy L. Ratliff,Mrg Robinson,T Shinka +8 more
TL;DR: In this chapter, some consensus guidelines for standardization of response and toxicity criteria for future studies are proposed and briefly review the existing literature which describes the results of intravesical chemotherapy and immunotherapy.
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Aspirin, ibuprofen, and other non-steroidal anti-inflammatory drugs in cancer prevention: a critical review of non-selective COX-2 blockade (review).
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Polo-like Kinase 1 Facilitates Loss of Pten Tumor Suppressor-induced Prostate Cancer Formation
X. Shawn Liu,Bing Song,Bennett D. Elzey,Timothy L. Ratliff,Stephen F. Konieczny,Liang Cheng,Nihal Ahmad,Xiaoqi Liu +7 more
TL;DR: It is demonstrated that Pten-depleted cells suffer from mitotic stress and that nuclear function of Pten, but not its phosphatase activity, is required to reverse this stress phenotype, which provides a mechanism explaining how cancer cells overcome oncogenesis-associated cellular stress.
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Use of graphene as protection film in biological environments
Weixia Zhang,Sudarat Lee,Sudarat Lee,Kelly McNear,Ting-Fung Chung,Seunghyun Lee,Kyunghoon Lee,Scott A. Crist,Timothy L. Ratliff,Zhaohui Zhong,Yong P. Chen,Chen Yang +11 more
TL;DR: Graphene effectively inhibits Cu surface from corrosion in different biological aqueous environments, and additional thiol derivatives assembled on graphene coated Cu surface can prominently enhance durability of sole graphene protection limited by the defects in graphene film.
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Avasimibe encapsulated in human serum albumin blocks cholesterol esterification for selective cancer treatment.
TL;DR: This study provides an effective approach for selective cancer chemotherapy by targeting altered cholesterol metabolism of cancer cells by targeting acyl-CoA cholesterol acyltransferase-1 (ACAT-1)-mediated cholesterol esterification.