T
Todd R. Klaenhammer
Researcher at North Carolina State University
Publications - 352
Citations - 32341
Todd R. Klaenhammer is an academic researcher from North Carolina State University. The author has contributed to research in topics: Lactobacillus acidophilus & Bacteriophage. The author has an hindex of 86, co-authored 352 publications receiving 30387 citations. Previous affiliations of Todd R. Klaenhammer include University of North Carolina at Chapel Hill.
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Journal ArticleDOI
Genetic organization and sequence of the region encoding integrative functions from Lactobacillus gasseri temperate bacteriophage φadh
TL;DR: A 2.0-kb fragment from the Lactobacillus gasseri temperate bacteriophage phi adh contained the essential genetic determinants for site-specific integration.
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Characterization of Lactobacillus gasseri isolates from a breast-fed infant.
Luciana Rodrigues da Cunha,Célia Lucia de Luces Fortes Ferreira,Evelyn Durmaz,Yong Jun Goh,Rosemary Sanozky-Dawes,Todd R. Klaenhammer +5 more
TL;DR: This study identified and characterized recently isolated L. gasseri strains from faeces of a breast fed infant as potential probiotic candidates for use in the human milk banks in Brazil and evaluated their safety and probiotic potential, in vitro.
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Development of bacteriophage-resistant strains of lactic acid bacteria.
TL;DR: The various phage defence systems that are naturally present in lactococci, their individual and combined effects, and the genetic strategies which are currently available to construct phageinsensitive strains for dairy fermentations are described.
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Genome Sequence and Characteristics of Lrm1, a Prophage from Industrial Lactobacillus rhamnosus Strain M1
Evelyn Durmaz,Michael J. Miller,M. Andrea Azcarate-Peril,Stephen P. Toon,Todd R. Klaenhammer +4 more
TL;DR: The presence of a defective prophage in an industrial strain could provide superinfection immunity to the host but could also contribute DNA in recombination events to produce new phages potentially infective for the host strain in a large-scale fermentation environment.
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High-Frequency Plasmid Transduction by Lactobacillus gasseri Bacteriophage φadh
Raúl R. Raya,Todd R. Klaenhammer +1 more
TL;DR: DNA hybridization analysis of p TRK170-transducing phage particles revealed that pTRK170 had integrated into the phiadh genome, suggesting that recombination between homologous sequences present in phage and plasmid DNAs was responsible for the formation of high-frequency transducingphage particles.