Todd R. Klaenhammer

TL;DR: The scientists and clinical investigators belonging to the Board of Directors of the International Scientific Association for Probiotics and Prebiotics (ISAPP) are concerned that claims supported by solid scientific evidence are also being rejected, and there is a lack of clarity regarding the criteria – from study design through wording of the claim – for a dossier suitable for a positive regulatory opinion.

TL;DR: Insight at the molecular and cellular levels contributed to the understanding of the interplay of a synbiotic composed of NCFM and raffinose with the host.

TL;DR: It is suggested that directed alteration of two of the L. acidophilus NCFM-Slps did not ameliorate LTA-induced pro-inflammatory signals and subsequent colitis, and this work elucidate the role of LTA in immune stimulation and induced colitis in vivo.

TL;DR: Results showed different levels of enzymatic overexpression associated with the cellular fraction and negligible amounts of activity present within the supernatant fraction of leaky lactococcal peptidases investigated in this study.

TL;DR: In this article, the plasmid pTR2030 and derivatives thereof which confer phage resistance to group N streptococci were described and compared to starter cultures containing the microorganisms.