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Tom J. Mabry

Bio: Tom J. Mabry is an academic researcher from University of Texas at Austin. The author has contributed to research in topics: Kaempferol & Sesquiterpene lactone. The author has an hindex of 42, co-authored 459 publications receiving 13375 citations. Previous affiliations of Tom J. Mabry include University of Illinois at Urbana–Champaign & Minia University.


Papers
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Dissertation
01 Jan 1960

4 citations

Book ChapterDOI
01 Jan 1970
TL;DR: A typical charcoal procedure for the preliminary purification of the flavonoid glycosides in a crude extract obtained from Baptisia lecontei plant material is presented in this paper.
Abstract: Charcoal is useful for the preliminary purification of a mixture of flavonoids, particularly flavonoid glycosides, which are usually present in a crude aqueous or aqueous-methanolic extract of plant material [1]. The charcoal procedure described below separates flavonoids from most non-aromatic plant constituents such as the common carbohydrates. The method is especially useful for flavonoid glycosides which are readily recovered almost quantitatively from the charcoal with water containing 7% phenol (i. e. a saturated aqueous solution at room temperature). Although many aglycones can also be recovered, at least in part, from the charcoal, the procedure is not recommended for their purification. Aglycones can often be extracted directly from a crude syrup obtained from a plant extract with a solvent such as ethyl acetate, while their complete recovery from charcoal many require the use of pyridine as eluent. A typical charcoal procedure is presented below for the preliminary purification of the flavonoids in a crude extract obtained from Baptisia lecontei plant material.

4 citations


Cited by
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Journal ArticleDOI
TL;DR: The factors underlying the influence of the different classes of polyphenols in enhancing their resistance to oxidation are discussed and support the contention that the partition coefficients of the flavonoids as well as their rates of reaction with the relevant radicals define the antioxidant activities in the lipophilic phase.

8,513 citations

Journal ArticleDOI
TL;DR: A revised and updated classification for the families of the flowering plants is provided in this paper, which includes Austrobaileyales, Canellales, Gunnerales, Crossosomatales and Celastrales.

7,299 citations

Journal Article
TL;DR: Western medicine has not yet used flavonoids therapeutically, even though their safety record is exceptional, and suggestions are made where such possibilities may be worth pursuing.
Abstract: Flavonoids are nearly ubiquitous in plants and are recognized as the pigments responsible for the colors of leaves, especially in autumn. They are rich in seeds, citrus fruits, olive oil, tea, and red wine. They are low molecular weight compounds composed of a three-ring structure with various substitutions. This basic structure is shared by tocopherols (vitamin E). Flavonoids can be subdivided according to the presence of an oxy group at position 4, a double bond between carbon atoms 2 and 3, or a hydroxyl group in position 3 of the C (middle) ring. These characteristics appear to also be required for best activity, especially antioxidant and antiproliferative, in the systems studied. The particular hydroxylation pattern of the B ring of the flavonoles increases their activities, especially in inhibition of mast cell secretion. Certain plants and spices containing flavonoids have been used for thousands of years in traditional Eastern medicine. In spite of the voluminous literature available, however, Western medicine has not yet used flavonoids therapeutically, even though their safety record is exceptional. Suggestions are made where such possibilities may be worth pursuing.

4,663 citations

Journal ArticleDOI
TL;DR: In this article, two complementary colorimetric methods, aluminum chloride method and 2,4-dini trophenylhydrazine method, were used to determine the real content of total flavonoids in propolis.

3,899 citations

Journal ArticleDOI
TL;DR: Several high-quality investigations have examined the relationship between flavonoid structure and antibacterial activity and these are in close agreement, and future studies may allow the development of a pharmacologically acceptable antimicrobial agent or class of agents.

3,630 citations