T
Tomas Hudlicky
Researcher at Brock University
Publications - 461
Citations - 11149
Tomas Hudlicky is an academic researcher from Brock University. The author has contributed to research in topics: Total synthesis & Toluene dioxygenase. The author has an hindex of 51, co-authored 460 publications receiving 10540 citations. Previous affiliations of Tomas Hudlicky include Procter & Gamble & University of Geneva.
Papers
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Recent advances in process development for opiate-derived pharmaceutical agents
TL;DR: In this paper, a short review summarizes the process development for the synthesis of buprenorphine, naltrexone, naloxone, and nalbuphine from naturally occurring opiates such as thebaine and oripa.
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Synthesis of C-1 homologues of pancratistatin and their preliminary biological evaluation.
TL;DR: The synthesis of two C-1 analogues of pancratistatin has been accomplished in 17 steps from bromobenzene and exhibited promising activity in several human cancer cell lines.
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Synthesis of beta -methoxy enones via a new two-carbon extension of carboxylic acids
Tomas Hudlicky,Horacio F. Olivo,Michael George Natchus,Eleuterio F. Umpierrez,Enrique Pandolfi,Carla Volonterio +5 more
Patent
Process for preparing a morphinan derivative
Tomas Hudlicky,Gabor Butora +1 more
TL;DR: In this paper, a process for preparing a morphinan derivative, by providing a dihydrofuranyl bridged tetracycle halide of the formula (19) wherein X is halogen, R is an alkyl group of from 1 to about 10 carbon atoms, and R 1 is a protecting group, was described.
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Inositol synthesis : concise preparation of l-chiro-inositol and muco-inositol from a common intermediate
Larry E. Brammer,Tomas Hudlicky +1 more
TL;DR: Fully stereoselective large-scale syntheses have been attained for l - chiro -inositol (2 ) and muco -inotol (3 ) by means of controlled peripheral oxygenation of cyclohexadiene diol as mentioned in this paper.