T
Tomas Hudlicky
Researcher at Brock University
Publications - 461
Citations - 11149
Tomas Hudlicky is an academic researcher from Brock University. The author has contributed to research in topics: Total synthesis & Toluene dioxygenase. The author has an hindex of 51, co-authored 460 publications receiving 10540 citations. Previous affiliations of Tomas Hudlicky include Procter & Gamble & University of Geneva.
Papers
More filters
Journal ArticleDOI
Formal total synthesis of (–)- and (+)-balanol: two complementary enantiodivergent routes from vinyloxiranes and vinylaziridines
TL;DR: In this article, a regioselective opening of 1,2-epoxycyclohex-3-ene with a chiral-auxiliary version of the Burgess reagent was used to provide a diastereomeric pair of cis-fused cyclic sulfamidates, which were transformed to trans-amino benzoates with ammonium benzoate and converted to (−)-2 and (+)-2 by oxidative cleavage and reductive amination.
Journal ArticleDOI
Two topologically distinct total syntheses of (.+-.)-sarkomycin
TL;DR: Synthese soit par cycloaddition intramoleculaire de la diazo-2 nonadiene-6,8one-3, soit a partir d'une cyclopenta [c] furannone
Journal ArticleDOI
Directed evolution of the dioxygenase complex for the synthesis of furanone flavor compounds
TL;DR: A directed evolution approach was taken to increase the substrate specificity and selectivity of the toluene dioxygenase enzyme system and to improve the efficiency of the enzymatic step.
Journal ArticleDOI
Chemoenzymic Synthesis of D-erythro- and L-threo-C18-Sphingosines
Journal ArticleDOI
Selective cytotoxicity against human osteosarcoma cells by a novel synthetic C-1 analogue of 7-deoxypancratistatin is potentiated by curcumin.
TL;DR: A new window in combination therapy is illustrated, utilizing a novel synthetic analogue of PST with the natural compound CC, for the treatment of OS.