T
Tomas Hudlicky
Researcher at Brock University
Publications - 461
Citations - 11149
Tomas Hudlicky is an academic researcher from Brock University. The author has contributed to research in topics: Total synthesis & Toluene dioxygenase. The author has an hindex of 51, co-authored 460 publications receiving 10540 citations. Previous affiliations of Tomas Hudlicky include Procter & Gamble & University of Geneva.
Papers
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Journal ArticleDOI
Design Constraints in Practical Syntheses of Complex Molecules: Current Status, Case Studies with Carbohydrates and Alkaloids, and Future Perspectives.
Journal ArticleDOI
Toluene Dioxygenase-Mediated cis-Dihydroxylation of Aromatics in Enantioselective Synthesis. Asymmetric Total Syntheses of Pancratistatin and 7-Deoxypancratistatin, Promising Antitumor Agents1
TL;DR: In this article, the coupling of a higher order cyanocuprate (derived by ortho-metalation from N,N-dimethyl-2-[(tert-butyldimethylsilyl)oxy]-3,4-(methylenedioxy)benzamide) with aziridine 7 to generate 28 contains the carbon framework of the title alkaloid.
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Microbial oxidation of chloroaromatics in the enantiodivergent synthesis of pyrrolizidine alkaloids: trihydroxyheliotridanes
TL;DR: Both enantiomers of the pyrrolizidine alkaloid trihydroxyheliotridane 1 have been prepared in an efficient and stereocontrolled fashion in 10 steps as discussed by the authors.
Book
Organic Synthesis: Theory and Applications
TL;DR: The role of organic synthesis in the generation of molecular diversity was discussed in this paper. But this work focused on the synthesis of cyclobutanes, and not on higher terpenes.
Journal ArticleDOI
Enantioselective synthesis through microbial oxidation of arenes. 1. Efficient preparation of terpene and prostanoid synthons
TL;DR: Le cis-toluenediol est obtenu par biodegradation du toluene par Pseudomonas putida, souche 39D, and est un substrat pour la synthese de prostaglandine.