T
Tomas Hudlicky
Researcher at Brock University
Publications - 461
Citations - 11149
Tomas Hudlicky is an academic researcher from Brock University. The author has contributed to research in topics: Total synthesis & Toluene dioxygenase. The author has an hindex of 51, co-authored 460 publications receiving 10540 citations. Previous affiliations of Tomas Hudlicky include Procter & Gamble & University of Geneva.
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Journal ArticleDOI
Microbial oxidation of aromatics in enantiocontrolled synthesis. Part 1. Expedient and general asymmetric synthesis of inositols and carbohydrates via an unusual oxidation of a polarized diene with potassium permanganate
Tomas Hudlicky,Martin Mandel,Jacques Rouden,Robert S. Lee,Bryan Bachmann,Travis Dudding,Kenneth J. Yost,Joseph S. Merola +7 more
TL;DR: In this paper, a general design of carbohydrates and cyclitols from biocatalytically derived synthons is described, and a mechanism for this transformation is proposed, placed in context with the only four reported examples of this reaction in the literature.
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Stereocontrolled total synthesis of pentalenenes via [2 + 3] and [4 + 1] cyclopentene annulation methodologies
TL;DR: Preparation en huit etapes du pentalenenes et de l'epipentalenene a partir de la dimethyl-7,7 bicyclo [3.3.0] octene-1one-3
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Rational design of aza sugars via biocatalysis : mannojirimycin and other glycosidase inhibitors
TL;DR: Mannojirymicin 2a, its C-5 epimer 13, and mannosidase inhibitor 3a have been synthesized from chlorobenzene via enzymatic hydroxylation followed by stereoselective amination and oxidative cleavage of the l-chlorocyclohexa-4,S-diene-2,3-diol.
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Intramolecular [4 + 1] pyrroline annulation via azide-diene cycloadditions. 2. Formal stereoselective total syntheses of (.+-.)-platynecine, (.+-.)-hastanecine, (.+-.)-turneforcidine, and (.+-.)-dihydroxyheliotridane
TL;DR: Cycloaddition d'azido-8 oxo-6 octadiene-2,4oate de methyle en hydroxy-4 aza-1bicyclo [3.1.0] hexaneacrylate-6 of methyle que l'on transforme ensuite en oxo 7 pyrrolizinecarboxylates-1
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Intramolecular cyclopentene annulation. 3. Synthesis and carbon-13 nuclear magnetic resonance spectroscopy of bicyclic cyclopentene lactones as potential perhydroazulene and/or monoterpene synthons
TL;DR: In this article, the cyclopropanation interne de diazoacetates de pentadiene-2,4 yle ou dhexadiene -2, 4 yle and diazomalonates de methyle et d'hexadienes-2.4 yl ou Pentadiene 2, 4 l ou 2.4 l yl suivie de pyrolyse des vinyl-4 perhydro cycloprocessa [c] furannones-1 obtenues conduit aux cyclopenta.