T
Tomas Hudlicky
Researcher at Brock University
Publications - 461
Citations - 11149
Tomas Hudlicky is an academic researcher from Brock University. The author has contributed to research in topics: Total synthesis & Toluene dioxygenase. The author has an hindex of 51, co-authored 460 publications receiving 10540 citations. Previous affiliations of Tomas Hudlicky include Procter & Gamble & University of Geneva.
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Journal ArticleDOI
Use of Electrochemical Methods as an Alternative to Tin Reagents for the Reduction of Vinyl Halides in Inositol Synthons.
Tomas Hudlicky,Christopher D. Claeboe,Larry E. Brammer,Lukasz Koroniak,Gabor Butora,Ion Ghiviriga +5 more
TL;DR: Electrochemical methods provide for selective reduction of vinyl iodides over vinyl bromides, with better yields than analogous tin methodology.
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Direct biooxidation of arenes to corresponding catechols with E. coli JM109 (pDTG602). Application to synthesis of combretastatins A-1 and B-1
TL;DR: In this paper, a convergent synthesis of combretastatins A-1 and B-1 was achieved via coupling of biocatalytically generated p-bromomethoxycatechol with trimethoxyphenylacetylene.
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Concise syntheses of 1,2-L-chiro-inositol conjugates and oligomers–a novel class of saccharide mimics with promising molecular properties
Tomas Hudlicky,Khalil A. Abboud,Joel Bolonick,Rakesh Maurya,Michelle L. Stanton,Andrew J. Thorpe +5 more
TL;DR: Calcium complexes with novel amino-inositol conjugates to form secondary extended helical structures are reported.
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Synthesis and biological evaluation of conduritol and conduramine analogs
TL;DR: A number of dimeric conduritol and conduramine analogs have been synthesized from naphthalene via a combination of enzymatic and chemical methods to give oxygenated derivatives with high stereo- and regiocontrol in few steps.
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Synthesis and biological evaluation of unnatural derivatives of narciclasine: 7-aza-nornarciclasine and its N-oxide.
TL;DR: Several unnatural derivatives of narciclasine were prepared in which the C-7 carbon was replaced with nitrogen and the 7-aza derivative and its N-oxide were prepared by the coupling of iodopicolinic acid with a conduramine unit derived chemoenzymatically from bromobenzene.