T
Tongtong He
Publications - 3
Citations - 583
Tongtong He is an academic researcher. The author has contributed to research in topics: Outbreak & Lytic cycle. The author has an hindex of 3, co-authored 3 publications receiving 418 citations.
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Journal ArticleDOI
Fatal swine acute diarrhoea syndrome caused by an HKU2-related coronavirus of bat origin.
Peng Zhou,Hang Fan,Tian Lan,Xing-Lou Yang,Weifeng Shi,Wei Zhang,Yan Zhu,Ya-Wei Zhang,Qingmei Xie,Shailendra Mani,Xiao-Shuang Zheng,Bei Li,Jinman Li,Hua Guo,Guangqian Pei,Xiaoping An,Jun-Wei Chen,Ling Zhou,Kai-jie Mai,Zixian Wu,Di Li,Danielle E. Anderson,Libiao Zhang,Shi-Yue Li,Zhiqiang Mi,Tongtong He,Feng Cong,Pengju Guo,Ren Huang,Yun Luo,Xiang-Ling Liu,Jing Chen,Yong Huang,Qiang Sun,Xianglilan Zhang,Yuan-Yuan Wang,Shaozhen Xing,Yan-Shan Chen,Yuan Sun,Juan Li,Peter Daszak,Lin-Fa Wang,Zhengli Shi,Yigang Tong,Jingyun Ma +44 more
TL;DR: Analysis of viral samples from deceased piglets shows that a bat coronav virus was responsible for an outbreak of fatal disease in China and highlights the importance of the identification of coronavirus diversity and distribution in bats in order to mitigate future outbreaks of disease.
Journal ArticleDOI
Identification of a lytic Pseudomonas aeruginosa phage depolymerase and its anti-biofilm effect and bactericidal contribution to serum
Liyuan Mi,Yannan Liu,Can Wang,Tongtong He,Shan Gao,Shaozhen Xing,Yong Huang,Hang Fan,Xianglilan Zhang,Wengong Yu,Zhiqiang Mi,Yigang Tong,Changqing Bai,Feng Han +13 more
TL;DR: Results showed that the phage-derived depolymerase-like protein has the potential to be developed into an anti-microbial agent that targets P. aeruginosa.
Journal ArticleDOI
An Integrative Analysis Reveals a Central Role of P53 Activation via MDM2 in Zika Virus Infection Induced Cell Death.
Yue Teng,Shufeng Liu,Xiaocan Guo,Liu Shuxia,Yuan Jin,Tongtong He,Dehua Bi,Pei Zhang,Baihan Lin,Xiaoping An,Dan Feng,Mi Zhiqiang,Yigang Tong +12 more
TL;DR: The bioinformatics findings in this study show that P53 is the hub of the genetic regulatory network for ZikV-related and microcephaly-associated proteins, and imply that the ZIKV capsid protein interacts with mouse double-minute-2 homolog (MDM2), which is involved in the P53-mediated apoptosis pathway, activating the death of infected neural cells.