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Trushar R. Patel

Researcher at University of Lethbridge

Publications -  103
Citations -  3274

Trushar R. Patel is an academic researcher from University of Lethbridge. The author has contributed to research in topics: RNA & Small-angle X-ray scattering. The author has an hindex of 26, co-authored 92 publications receiving 2416 citations. Previous affiliations of Trushar R. Patel include University of Calgary & University of Birmingham.

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Dynamic light scattering: a practical guide and applications in biomedical sciences.

TL;DR: Evidence of the usefulness of DLS to study the homogeneity of proteins, nucleic acids, and complexes of protein–protein or protein–nucleic acid preparations, as well as to study protein–small molecule interactions is provided.

EVpedia: A community web portal for extracellular vesicles research

TL;DR: In this paper, the authors present an improved version of EVpedia, a public database for extracellular vesicles (EVs) research, which contains a database of publications and vesicular components, identification of orthologous vesicle components, bioinformatic tools and a personalized function.
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Vimentin coil 1A-A molecular switch involved in the initiation of filament elongation.

TL;DR: The introduction of a single stabilizing point mutation at an a or a d position did induce the formation of a stable dimer as demonstrated by sedimentation equilibrium experiments, and the dimeric oligomerisation state of the Y117L peptide was confirmed by X-ray crystallography, which yielded a structure with a genuine coiled-coil geometry.
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Molecular mechanisms of viral hepatitis induced hepatocellular carcinoma.

TL;DR: An overview of HBV, HCV and HDV molecular biology is provided to highlight specific viral-associated oncogenic mechanisms and common molecular pathways deregulated in HCC, and current as well as emerging treatments for HCC.
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Immunological and Structural Properties of a Pectic Polymer from Glinus Oppositifolius

TL;DR: The aim of this paper was to further elucidate the structure and the immunomodulating properties of the pectic polymer GOA2, previously isolated from Glinus oppositifolius, and show a broad degree of polydispersity and a rhamnogalacturonan-I type structure.