T
Tugba Boyunegmez Tumer
Researcher at Çanakkale Onsekiz Mart University
Publications - 33
Citations - 1335
Tugba Boyunegmez Tumer is an academic researcher from Çanakkale Onsekiz Mart University. The author has contributed to research in topics: Medicine & Chemistry. The author has an hindex of 15, co-authored 29 publications receiving 729 citations. Previous affiliations of Tugba Boyunegmez Tumer include Rutgers University & Middle East Technical University.
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Journal ArticleDOI
Piper Species: A Comprehensive Review on Their Phytochemistry, Biological Activities and Applications.
Bahare Salehi,Zainul Amiruddin Zakaria,Rabin Gyawali,Salam A. Ibrahim,Jovana Rajkovic,Zabta Khan Shinwari,Tariq Khan,Javad Sharifi-Rad,Adem Ozleyen,Elif Turkdonmez,Marco Valussi,Tugba Boyunegmez Tumer,Lianet Monzote Fidalgo,Miquel Martorell,William N. Setzer +14 more
TL;DR: The functional properties of Piper plants/extracts/active components the antiproliferative, anti-inflammatory, and neuropharmacological activities of the extracts and extract-derived bioactive constituents are thought to be key effects for the protection against chronic conditions.
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Insights on the Use of α-Lipoic Acid for Therapeutic Purposes
Bahare Salehi,Yakup Berkay Yılmaz,Gizem Antika,Tugba Boyunegmez Tumer,Mohamad Fawzi Mahomoodally,Devina Lobine,Muhammad Akram,Muhammad Riaz,Esra Capanoglu,Farukh Sharopov,Natália Martins,William C. Cho,Javad Sharifi-Rad +12 more
TL;DR: Improved formulations can increase both ALA absorption and bioavailability, leading to a raise in therapeutic efficacy, and Interestingly, ALA bioavailability will be dependent on age, while no difference has been found for gender.
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Isothiocyanate‐rich Moringa oleifera extract reduces weight gain, insulin resistance, and hepatic gluconeogenesis in mice
Carrie Waterman,Patricio Rojas-Silva,Tugba Boyunegmez Tumer,Tugba Boyunegmez Tumer,Peter Kuhn,Allison J. Richard,Shawna E. Wicks,Jacqueline M. Stephens,Zhong Wang,Randy Mynatt,William T. Cefalu,Ilya Raskin +11 more
TL;DR: Data suggest that MICs are the main anti-obesity and anti-diabetic bioactives of MC, and that they exert their effects by inhibiting rate-limiting steps in liver gluconeogenesis resulting in direct or indirect increase in insulin signaling and sensitivity.
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Impact of Natural Compounds on Neurodegenerative Disorders: From Preclinical to Pharmacotherapeutics.
Mehdi Sharifi-Rad,Chintha Lankatillake,Daniel A. Dias,Anca Oana Docea,Mohamad Fawzi Mahomoodally,Devina Lobine,Paul L. Chazot,Begum Kurt,Tugba Boyunegmez Tumer,Ana Moreira,Farukh Sharopov,Miquel Martorell,Natália Martins,William C. Cho,Daniela Calina,Javad Sharifi-Rad +15 more
TL;DR: The mechanisms of action of some of the major herbal products with potential in the treatment of NDDs are reviewed according to their molecular targets, as well as their regional sources (Asia, America and Africa).
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Natural Products and Synthetic Analogs as a Source of Antitumor Drugs.
Javad Sharifi-Rad,Adem Ozleyen,Tugba Boyunegmez Tumer,Charles Oluwaseun Adetunji,Nasreddine El Omari,Abdelaali Balahbib,Yasaman Taheri,Abdelhakim Bouyahya,Miquel Martorell,Natália Martins,William C. Cho +10 more
TL;DR: The utilization of natural products as a source of antitumor drugs with abundant pool of diverse chemicals and pharmacologically active compounds is presented.