Paul L. Chazot

TL;DR: The H3R is an autoreceptor and heteroreceptor providing negative feedback on histaminergic and inhibition on other neurons, a block of these actions promotes waking and the development of anti-inflammatory drugs is anticipated.

TL;DR: The Concise Guide to PHARMACOLOGY 2021/22 as mentioned in this paper provides concise overviews, mostly in tabular format, of the key properties of nearly 1900 human drug targets with an emphasis on selective pharmacology (where available), plus links to the open access knowledgebase source of drug targets and their ligands.

TL;DR: This work investigates the possibility that H4 receptors may be expressed in both the human and mouse CNS, and binds several neuroactive drugs, including amitriptyline and clozapine.

TL;DR: The historical developments and the molecular and biochemical pharmacology of the H4 receptor and its role in immune function are summarized.

TL;DR: There is no evidence that melissa aromatherapy is superior to placebo or donepezil, in the treatment of agitation in people with Alzheimer’s disease, but the sizeable improvement in the placebo group emphasizes the potential non-specific benefits of touch and interaction.