T
Tung On Yau
Researcher at Nottingham Trent University
Publications - 37
Citations - 1958
Tung On Yau is an academic researcher from Nottingham Trent University. The author has contributed to research in topics: Colorectal cancer & Cancer. The author has an hindex of 13, co-authored 34 publications receiving 1233 citations. Previous affiliations of Tung On Yau include The Chinese University of Hong Kong.
Papers
More filters
Journal ArticleDOI
Metagenomic analysis of faecal microbiome as a tool towards targeted non-invasive biomarkers for colorectal cancer
Jun Yu,Qiang Feng,Sunny H. Wong,Dongya Zhang,Qiaoyi Liang,Youwen Qin,Longqing Tang,Hui Zhao,Jan Stenvang,Yanli Li,Xiaokai Wang,Xiaoqiang Xu,Ning Chen,William K.K. Wu,Jumana Y. Al-Aama,Hans Jørgen Nielsen,Pia Kiilerich,Benjamin A. H. Jensen,Tung On Yau,Zhou Lan,Huijue Jia,Junhua Li,Liang Xiao,Thomas Y.T. Lam,Siew C. Ng,Alfred S. L. Cheng,Vincent Wai-Sun Wong,Francis K.L. Chan,Xun Xu,Huanming Yang,Lise Madsen,Lise Madsen,Christian Datz,Herbert Tilg,Jian Wang,Nils Brünner,Karsten Kristiansen,Manimozhiyan Arumugam,Joseph J.Y. Sung,Jun Wang +39 more
TL;DR: The first metagenomic profiling study of CRC faecal microbiomes is presented to discover and validate microbial biomarkers in ethnically different cohorts, and to independently validate selected biomarkers using an affordable clinically relevant technology.
Journal ArticleDOI
CXCL10 plays a key role as an inflammatory mediator and a non-invasive biomarker of non-alcoholic steatohepatitis
Xiang Zhang,Jiayun Shen,Kwan Man,Eagle S. H. Chu,Tung On Yau,Joanne C.Y. Sung,Minnie Y.Y. Go,Jun Deng,Liwei Lu,Vincent Wai-Sun Wong,Joseph J.Y. Sung,Geoffrey C. Farrell,Jun Yu +12 more
TL;DR: It is demonstrated for the first time that CXCL10 plays a pivotal role in the pathogenesis of experimental steatohepatitis and was an independent risk factor for NASH patients.
Journal ArticleDOI
A novel faecal Lachnoclostridium marker for the non-invasive diagnosis of colorectal adenoma and cancer.
Jessie Qiaoyi Liang,Tong Li,Geicho Nakatsu,Ying-Xuan Chen,Tung On Yau,Eagle S. H. Chu,Sunny H. Wong,Chun Ho Szeto,Siew C. Ng,Francis K.L. Chan,Jing-Yuan Fang,Joseph J.Y. Sung,Jun Yu +12 more
TL;DR: Faecal m3 and Fn were significantly increased from normal to adenoma to CRC, and the combination of m3 with Fn, Ch, Bacteroides clarus and FIT performed best for diagnosing CRC.
Journal ArticleDOI
Identification of microRNA-135b in Stool as a Potential Noninvasive Biomarker for Colorectal Cancer and Adenoma
Chung Wah Wu,Siew C. Ng,Yujuan Dong,Linwei Tian,Simon S.M. Ng,Wing Wa Leung,Wai Tak Law,Tung On Yau,Francis K.L. Chan,Joseph J.Y. Sung,Jun Yu +10 more
TL;DR: Stool-based miR-135b can be used as a noninvasive biomarker for the detection of CRC and advanced adenoma in patients with IBD compared with controls.
Journal ArticleDOI
Management of chronic hepatitis B infection: current treatment guidelines, challenges, and new developments.
TL;DR: An updated practical approach to guide the clinical management of CHB is presented, and the evidence for the efficacy of various antiviral agents is systematically reviewed.