J
Jumana Y. Al-Aama
Researcher at King Abdulaziz University
Publications - 124
Citations - 10148
Jumana Y. Al-Aama is an academic researcher from King Abdulaziz University. The author has contributed to research in topics: Exome sequencing & Induced pluripotent stem cell. The author has an hindex of 30, co-authored 118 publications receiving 7622 citations.
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Journal ArticleDOI
Dynamics and Stabilization of the Human Gut Microbiome during the First Year of Life.
Fredrik Bäckhed,Fredrik Bäckhed,Josefine Roswall,Yangqing Peng,Qiang Feng,Huijue Jia,Petia Kovatcheva-Datchary,Yin Li,Yan Xia,Hailiang Xie,Huanzi Zhong,Muhammad Tanweer Khan,Jianfeng Zhang,Junhua Li,Liang Xiao,Jumana Y. Al-Aama,Dongya Zhang,Ying Shiuan Lee,Dorota Ewa Kotowska,Camilla Colding,Valentina Tremaroli,Ye Yin,Stefan Bergman,Xun Xu,Lise Madsen,Lise Madsen,Karsten Kristiansen,Jovanna Dahlgren,Jun Wang +28 more
TL;DR: The gut microbiota of infants delivered by C-section showed significantly less resemblance to their mothers and nutrition had a major impact on early microbiota composition and function, with cessation of breast-feeding, rather than introduction of solid food, being required for maturation into an adult-like microbiota.
Journal ArticleDOI
An integrated catalog of reference genes in the human gut microbiome
Junhua Li,Huijue Jia,Xianghang Cai,Huanzi Zhong,Qiang Feng,Shinichi Sunagawa,Manimozhiyan Arumugam,Jens Roat Kultima,Edi Prifti,Trine Nielsen,Agnieszka S. Juncker,Chaysavanh Manichanh,Bing Chen,Wenwei Zhang,Florence Levenez,Juan Wang,Xun Xu,Liang Xiao,Suisha Liang,Dongya Zhang,Zhaoxi Zhang,Weineng Chen,Hailong Zhao,Jumana Y. Al-Aama,Sherif Edris,Huanming Yang,Jian Wang,Torben Hansen,Henrik Nielsen,Søren Brunak,Karsten Kristiansen,Francisco Guarner,Oluf Pedersen,Joël Doré,S. Dusko Ehrlich,Peer Bork,Jun Wang +36 more
TL;DR: The integrated gene catalog (IGC) is established comprising 9,879,896 genes, which includes close-to-complete sets of genes for most gut microbes, which are also of considerably higher quality than in previous catalogs.
Journal ArticleDOI
The oral and gut microbiomes are perturbed in rheumatoid arthritis and partly normalized after treatment
Xuan Zhang,Dongya Zhang,Huijue Jia,Qiang Feng,Donghui Wang,Di Liang,Xiangni Wu,Junhua Li,Longqing Tang,Yin Li,Zhou Lan,Bing Chen,Yanli Li,Huanzi Zhong,Hailiang Xie,Zhuye Jie,Weineng Chen,Shanmei Tang,Xiaoqiang Xu,Xiaokai Wang,Xianghang Cai,Liu Sheng,Yan Xia,Jiyang Li,Xingye Qiao,Jumana Y. Al-Aama,Hua Chen,Li Wang,Qingjun Wu,Fengchun Zhang,Wenjie Zheng,Yongzhe Li,Mingrong Zhang,Guangwen Luo,Wenbin Xue,Liang Xiao,Jun Li,Wanting Chen,Xun Xu,Ye Yin,Huanming Yang,Jian Wang,Karsten Kristiansen,Liang Liu,Ting Li,Qingchun Huang,Yingrui Li,Jun Wang +47 more
TL;DR: Altered alterations in the gut, dental or saliva microbiome distinguished individuals with RA from healthy controls, were correlated with clinical measures and could be used to stratify individuals on the basis of their response to therapy.
Journal ArticleDOI
Gut microbiome development along the colorectal adenoma-carcinoma sequence.
Qiang Feng,Suisha Liang,Huijue Jia,Andreas Stadlmayr,Longqing Tang,Zhou Lan,Dongya Zhang,Huihua Xia,Xiaoying Xu,Zhuye Jie,Lili Su,Xiaoping Li,Xin Li,Junhua Li,Liang Xiao,Ursula Huber-Schönauer,David Niederseer,Xun Xu,Jumana Y. Al-Aama,Huanming Yang,Jian Wang,Karsten Kristiansen,Manimozhiyan Arumugam,Herbert Tilg,Christian Datz,Jun Wang +25 more
TL;DR: It is suggested that faecal microbiome-based strategies may be useful for early diagnosis and treatment of colorectal adenoma or carcinoma and high intake of red meat relative to fruits and vegetables appears to associate with outgrowth of bacteria that might contribute to a more hostile gut environment.
Journal ArticleDOI
Metagenomic analysis of faecal microbiome as a tool towards targeted non-invasive biomarkers for colorectal cancer
Jun Yu,Qiang Feng,Sunny H. Wong,Dongya Zhang,Qiaoyi Liang,Youwen Qin,Longqing Tang,Hui Zhao,Jan Stenvang,Yanli Li,Xiaokai Wang,Xiaoqiang Xu,Ning Chen,William K.K. Wu,Jumana Y. Al-Aama,Hans Jørgen Nielsen,Pia Kiilerich,Benjamin A. H. Jensen,Tung On Yau,Zhou Lan,Huijue Jia,Junhua Li,Liang Xiao,Thomas Y.T. Lam,Siew C. Ng,Alfred S. L. Cheng,Vincent Wai-Sun Wong,Francis K.L. Chan,Xun Xu,Huanming Yang,Lise Madsen,Lise Madsen,Christian Datz,Herbert Tilg,Jian Wang,Nils Brünner,Karsten Kristiansen,Manimozhiyan Arumugam,Joseph J.Y. Sung,Jun Wang +39 more
TL;DR: The first metagenomic profiling study of CRC faecal microbiomes is presented to discover and validate microbial biomarkers in ethnically different cohorts, and to independently validate selected biomarkers using an affordable clinically relevant technology.