U
Ulrich Desselberger
Researcher at University of Cambridge
Publications - 9
Citations - 1647
Ulrich Desselberger is an academic researcher from University of Cambridge. The author has contributed to research in topics: Genome & Rotavirus. The author has an hindex of 7, co-authored 9 publications receiving 1467 citations.
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Journal ArticleDOI
Uniformity of rotavirus strain nomenclature proposed by the Rotavirus Classification Working Group (RCWG).
Jelle Matthijnssens,Max Ciarlet,Sarah M. McDonald,Houssam Attoui,Krisztián Bányai,J. Rodney Brister,Javier Buesa,Mathew D. Esona,Mary K. Estes,Jon R. Gentsch,Miren Iturriza-Gomara,Reimar Johne,Carl D. Kirkwood,Vito Martella,Peter P. C. Mertens,Osamu Nakagomi,Viviana Parreño,Mustafizur Rahman,Franco Maria Ruggeri,Linda J. Saif,Norma Santos,Andrej Steyer,Koki Taniguchi,John T. Patton,Ulrich Desselberger,Marc Van Ranst +25 more
TL;DR: With increasing numbers of complete RV genome sequences becoming available, a standardized RV strain nomenclature system is needed, and the RCWG proposes that individual RV strains are named as follows: RV group/species of origin/country of identification/common name/year of identification /G- and P-type.
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VP6-sequence-based cutoff values as a criterion for rotavirus species demarcation.
TL;DR: Indirect immunofluorescence techniques targeting the rotavirus (RV) protein VP6 are used to differentiate RV species and a potential new RV species, ADRV-N, has been described.
Journal ArticleDOI
Rotaviruses Associate with Cellular Lipid Droplet Components To Replicate in Viroplasms, and Compounds Disrupting or Blocking Lipid Droplets Inhibit Viroplasm Formation and Viral Replication
Winsome Cheung,Michael Gill,Alessandro Esposito,Clemens F. Kaminski,Nathalie Courousse,Serge Chwetzoff,Germain Trugnan,Nandita Keshavan,Andrew M. L. Lever,Ulrich Desselberger +9 more
TL;DR: Chemical compounds interfering with LD formation decreased the number of viroplasms and inhibited dsRNA replication and the production of infectious progeny virus; this effect correlated with significant protection of cells from virus-associated cytopathicity.
Journal ArticleDOI
Immune Responses to Rotavirus Infection and Vaccination and Associated Correlates of Protection
TL;DR: The immune responses to natural RV infection and RV vaccination in both experimental animals and humans are considered as potential correlates of protection.
Journal ArticleDOI
Genomic analysis of codon, sequence and structural conservation with selective biochemical-structure mapping reveals highly conserved and dynamic structures in rotavirus RNAs with potential cis -acting functions
Wilson Li,Emily Manktelow,Johann C. von Kirchbach,Julia R. Gog,Ulrich Desselberger,Andrew M. L. Lever +5 more
TL;DR: Extensive in silico and in vitro analyses provide evidence of the conservation, complexity, multi-functionality and dynamics of rotavirus RNA structures which likely influence RNA replication, translation and genome packaging.