U
Ulrich H. von Andrian
Researcher at Harvard University
Publications - 287
Citations - 50562
Ulrich H. von Andrian is an academic researcher from Harvard University. The author has contributed to research in topics: Immune system & T cell. The author has an hindex of 115, co-authored 269 publications receiving 46535 citations. Previous affiliations of Ulrich H. von Andrian include Merck & Co. & Stanford University.
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Journal ArticleDOI
Lineage relationship and protective immunity of memory CD8 T cell subsets.
E. John Wherry,Volker Teichgräber,Todd C. Becker,David Masopust,Susan M. Kaech,Rustom Antia,Ulrich H. von Andrian,Rafi Ahmed +7 more
TL;DR: It is proposed that TCM and TEM do not necessarily represent distinct subsets, but are part of a continuum in a linear naive → effector → TEM → TCM differentiation pathway.
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T-cell priming by dendritic cells in lymph nodes occurs in three distinct phases
TL;DR: T-cell priming by DCs occurs in three successive stages: transient serial encounters during the first activation phase are followed by a second phase of stable contacts culminating in cytokine production, which makes a transition into a third phase of high motility and rapid proliferation.
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T-cell function and migration. Two sides of the same coin.
TL;DR: This review will concentrate on the migration of T cells, which are at the heart of most adaptive immune responses, since T cells respond to pathogens only on direct contact with pathogen-derived antigen.
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Compensation mechanism in tumor cell migration: mesenchymal–amoeboid transition after blocking of pericellular proteolysis
Katarina Wolf,Irina B. Mazo,Harry Leung,Katharina Engelke,Ulrich H. von Andrian,Elena I. Deryugina,Alex Y. Strongin,Eva B. Bröcker,Peter Friedl +8 more
TL;DR: The transition from proteolytic mesenchymal toward nonproteolytic amoeboid movement highlights a supramolecular plasticity mechanism in cell migration and further represents a putative escape mechanism in tumor cell dissemination after abrogation of pericellular proteolysis.
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Vitamin effects on the immune system: vitamins A and D take centre stage
TL;DR: The current understanding of the essential roles of vitamins in modulating a broad range of immune processes, such as lymphocyte activation and proliferation, T-helper-cell differentiation, tissue-specific lymphocyte homing, and the production of specific antibody isotypes and regulation of the immune response are presented.