U
Umberto DeGirolami
Researcher at University of Massachusetts Amherst
Publications - 40
Citations - 3783
Umberto DeGirolami is an academic researcher from University of Massachusetts Amherst. The author has contributed to research in topics: Ischemia & Cerebral blood flow. The author has an hindex of 24, co-authored 40 publications receiving 3697 citations. Previous affiliations of Umberto DeGirolami include University of Massachusetts Medical School.
Papers
More filters
Journal ArticleDOI
Thresholds of focal cerebral ischemia in awake monkeys
Thomas H. Jones,Richard Morawetz,Robert M. Crowell,Frank W. Marcoux,Stuart J. FitzGibbon,Umberto DeGirolami,Robert G. Ojemann +6 more
TL;DR: Some cases of acute hemiplegia, with blood flow in the paralysis range, might be improved by surgical revascularization, and studies of local CBF might help identify suitable cases for emergency revascularized.
Journal ArticleDOI
Tissue plasminogen activator reduces neurological damage after cerebral embolism
TL;DR: In vitro studies indicate that tissue plasminogen activator produced substantial lysis of clots at concentrations comparable to those expected in vivo, suggesting that this may be the mechanism of action of this drug.
Journal ArticleDOI
Endothelial dysfunction and the expression of endothelial nitric oxide synthetase in diabetic neuropathy, vascular disease, and foot ulceration.
Aristidis Veves,Cameron M. Akbari,James Primavera,Valerie M. Donaghue,Dimitrios Zacharoulis,J S Chrzan,Umberto DeGirolami,Frank W. LoGerfo,Roy Freeman +8 more
TL;DR: It is concluded that the endothelium-dependent and endothelial-independent vasodilations are impaired in diabetic patients predisposed to foot ulceration and that neuropathy is the main factor associated with this abnormality.
Journal ArticleDOI
HIV-associated disease of the nervous system: review of nomenclature and proposal for neuropathology-based terminology.
Herbert Budka,Clayton A. Wiley,Paul Kleihues,Juan Artigas,Arthur K. Asbury,Eun Sook Cho,David R. Cornblath,Mauro C. Dal Canto,Umberto DeGirolami,Dennis W. Dickson,Leon G. Epstein,Margaret M. Esiri,Felice Giangaspero,Georg Gosztonyi,Françoise Gray,John W. Griffin,Dominique Hénin,Yuzo Iwasaki,Robert S. Janssen,Richard T. Johnson,Peter L. Lantos,William D. Lyman,Justin C. McArthur,Kazuo Nagashima,Nancy S. Peress,Carol K. Petito,Richard W. Price,Roy H. Rhodes,Marc K. Rosenblum,Gérard Said,Francesco Scaravilli,Leroy R. Sharer,Harry V. Vinters +32 more
TL;DR: Herbert Budka 1, Clayton A. Wiley 2, Paul Kleihues 3, Juan Artigas 4, Arthur K. Asbury 5, Eun-Sook Cho 6, David R. Cornblath 7, Mauro C. Dal Canto 8, Umberto DeGirolami 9, Dennis Dickson 10, Leon G. Epstein 11, Margaret M. Esiri 12, Felice Giangaspero 13, Georg Gosztonyi 14,
Journal ArticleDOI
Neuropathology of Experimental Spinal Cord Ischemia in the Rabbit
Umberto DeGirolami,J A Zivin +1 more
TL;DR: The segmental topographic distribution of the lesion and its histologic characteristics are discussed in relation to two important pathophysiological mechanisms of injury in central nervous system ischemia: the microcirculatory network, which in turn governs the adequacy of collateral flow, and the differential susceptibility of cells in nervous tissue.