V
Vala G. Gudnadottir
Researcher at deCODE genetics
Publications - 4
Citations - 2611
Vala G. Gudnadottir is an academic researcher from deCODE genetics. The author has contributed to research in topics: Haplotype & Population. The author has an hindex of 4, co-authored 4 publications receiving 2509 citations.
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Journal ArticleDOI
Neuregulin 1 and Susceptibility to Schizophrenia
Hreinn Stefansson,Engilbert Sigurdsson,Valgerdur Steinthorsdottir,Soley Bjornsdottir,Thordur Sigmundsson,Shyamali Ghosh,J Brynjolfsson,Steinunn Gunnarsdottir,Omar Ivarsson,Thomas T. Chou,Omar Hjaltason,Birgitta Birgisdottir,Helgi Jonsson,Vala G. Gudnadottir,Elsa Gudmundsdottir,Asgeir Björnsson,Brynjolfur Ingvarsson,Andres Ingason,Sigmundur Sigfusson,Hronn Hardardottir,Richard P. Harvey,Richard P. Harvey,Donna Lai,Mingdong Zhou,Daniela Brunner,Vincent Mutel,Acuna Gonzalo,Greg Lemke,Jesus Sainz,Gardar Johannesson,Thorkell Andresson,Daniel F. Gudbjartsson,Andrei Manolescu,Michael L. Frigge,Mark E. Gurney,Augustine Kong,Jeffrey R. Gulcher,Hannes Petursson,Kari Stefansson +38 more
TL;DR: The results of a genomewide scan of schizophrenia families in Iceland show that schizophrenia maps to chromosome 8p, and extensive fine-mapping of the 8p locus and haplotype-association analysis identifies neuregulin 1 (NRG1) as a candidate gene for schizophrenia.
Journal ArticleDOI
A common inversion under selection in Europeans
Hreinn Stefansson,Agnar Helgason,Gudmar Thorleifsson,Valgerdur Steinthorsdottir,Gisli Masson,John Barnard,Adam Baker,Aslaug Jonasdottir,Andres Ingason,Vala G. Gudnadottir,Natasa Desnica,Andrew A. Hicks,Arnaldur Gylfason,Daniel F. Gudbjartsson,Gudrun M. Jonsdottir,Jesus Sainz,Kari Agnarsson,Birgitta Birgisdottir,Shyamali Ghosh,Adalheidur Olafsdottir,Jean-Baptiste Cazier,Kristleifur Kristjansson,Michael L. Frigge,Thorgeir E. Thorgeirsson,Jeffrey R. Gulcher,Augustine Kong,Kari Stefansson +26 more
TL;DR: It is shown that the H2 lineage is undergoing positive selection in the Icelandic population, such that carrier females have more children and have higher recombination rates than noncarriers.
Journal ArticleDOI
Identification of a novel neuregulin 1 at-risk haplotype in Han schizophrenia Chinese patients, but no association with the Icelandic/Scottish risk haplotype.
Tao Li,Hreinn Stefansson,Einar Gudfinnsson,G Cai,Xiehe Liu,Robin M. Murray,Valgerdur Steinthorsdottir,D Januel,Vala G. Gudnadottir,H. Petursson,Andres Ingason,Jeffrey R. Gulcher,Kari Stefansson,David A. Collier +13 more
TL;DR: Different haplotypes within the boundaries of the NRG1 gene may be associated with schizophrenia in the Han Chinese, including markers of a seven-marker haplotype at the 5′end of the gene found to be in excess in Icelandic and Scottish schizophrenia patients.
Journal ArticleDOI
Endometriosis is not associated with or linked to the GALT gene
Hreinn Stefansson,Arna Einarsdottir,Reynir Tómas Geirsson,Kristín Jónsdóttir,Gudlaug Sverrisdottir,Vala G. Gudnadottir,Steinunn Gunnarsdottir,Andrei Manolescu,Jeffrey R. Gulcher,Kari Stefansson +9 more
TL;DR: The experiments reported herein provide no evidence supporting involvement of the GALT locus in the development of endometriosis.