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Asgeir Björnsson
Researcher at deCODE genetics
Publications - 21
Citations - 5156
Asgeir Björnsson is an academic researcher from deCODE genetics. The author has contributed to research in topics: Stop codon & Open reading frame. The author has an hindex of 16, co-authored 21 publications receiving 4980 citations. Previous affiliations of Asgeir Björnsson include University of Iceland & Stockholm University.
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Journal ArticleDOI
Large recurrent microdeletions associated with schizophrenia
Hreinn Stefansson,Dan Rujescu,Sven Cichon,Olli Pietiläinen,Andres Ingason,Stacy Steinberg,Ragnheidur Fossdal,Engilbert Sigurdsson,Thordur Sigmundsson,Jacobine E. Buizer-Voskamp,Thomas Hansen,Thomas Hansen,Klaus D. Jakobsen,Klaus D. Jakobsen,Pierandrea Muglia,Clyde Francks,Paul M. Matthews,Arnaldur Gylfason,Bjarni V. Halldorsson,Daniel F. Gudbjartsson,Thorgeir E. Thorgeirsson,Asgeir Sigurdsson,Adalbjorg Jonasdottir,Aslaug Jonasdottir,Asgeir Björnsson,Sigurborg Mattiasdottir,Thorarinn Blondal,Magnús Haraldsson,Brynja B. Magnusdottir,Ina Giegling,Hans-Jürgen Möller,Annette M. Hartmann,Kevin V. Shianna,Dongliang Ge,Anna C. Need,Caroline Crombie,Gillian Fraser,Nicholas Walker,Jouko Lönnqvist,Jaana Suvisaari,Annamarie Tuulio-Henriksson,Tiina Paunio,T. Toulopoulou,Elvira Bramon,Marta Di Forti,Robin M. Murray,Mirella Ruggeri,Evangelos Vassos,Sarah Tosato,Muriel Walshe,Tao Li,Tao Li,Catalina Vasilescu,Thomas W. Mühleisen,August G. Wang,Henrik Ullum,Srdjan Djurovic,Ingrid Melle,Jes Olesen,Lambertus A. Kiemeney,Barbara Franke,Chiara Sabatti,Nelson B. Freimer,Jeffrey R. Gulcher,Unnur Thorsteinsdottir,Augustine Kong,Ole A. Andreassen,Roel A. Ophoff,Roel A. Ophoff,Alexander Georgi,Marcella Rietschel,Thomas Werge,Hannes Petursson,David Goldstein,Markus M. Nöthen,Leena Peltonen,Leena Peltonen,David A. Collier,David A. Collier,David St Clair,Kari Stefansson,Kari Stefansson +81 more
TL;DR: In a genome-wide search for CNVs associating with schizophrenia, a population-based sample was used to identify de novo CNVs by analysing 9,878 transmissions from parents to offspring and three deletions significantly associate with schizophrenia and related psychoses in the combined sample.
Journal ArticleDOI
Neuregulin 1 and Susceptibility to Schizophrenia
Hreinn Stefansson,Engilbert Sigurdsson,Valgerdur Steinthorsdottir,Soley Bjornsdottir,Thordur Sigmundsson,Shyamali Ghosh,J Brynjolfsson,Steinunn Gunnarsdottir,Omar Ivarsson,Thomas T. Chou,Omar Hjaltason,Birgitta Birgisdottir,Helgi Jonsson,Vala G. Gudnadottir,Elsa Gudmundsdottir,Asgeir Björnsson,Brynjolfur Ingvarsson,Andres Ingason,Sigmundur Sigfusson,Hronn Hardardottir,Richard P. Harvey,Richard P. Harvey,Donna Lai,Mingdong Zhou,Daniela Brunner,Vincent Mutel,Acuna Gonzalo,Greg Lemke,Jesus Sainz,Gardar Johannesson,Thorkell Andresson,Daniel F. Gudbjartsson,Andrei Manolescu,Michael L. Frigge,Mark E. Gurney,Augustine Kong,Jeffrey R. Gulcher,Hannes Petursson,Kari Stefansson +38 more
TL;DR: The results of a genomewide scan of schizophrenia families in Iceland show that schizophrenia maps to chromosome 8p, and extensive fine-mapping of the 8p locus and haplotype-association analysis identifies neuregulin 1 (NRG1) as a candidate gene for schizophrenia.
Journal ArticleDOI
Genome-wide association study of migraine implicates a common susceptibility variant on 8q22.1
Anttila,Hreinn Stefansson,Mikko Kallela,U. Todt,Gisela M. Terwindt,Calafato Ms,Dale R. Nyholt,Antigone S. Dimas,T. Freilinger,Bertram Müller-Myhsok,Artto,Michael Inouye,Kirsi Alakurtti,Mari A. Kaunisto,Eija Hämäläinen,de Vries B,AH Stam,Claudia M Weller,Axel Heinze,Katja Heinze-Kuhn,Ingrid Goebel,Guntram Borck,H. Gobel,Stacy Steinberg,Christiane Wolf,Asgeir Björnsson,Gudmundur H. Gudmundsson,M. Kirchmann,A. Hauge,Thomas Werge,Jean Schoenen,Johan G. Eriksson,Knut Hagen,Lars Jacob Stovner,Heinz Erich Wichmann,Thomas Meitinger,Michael Alexander,Susanne Moebus,Stefan Schreiber,Yurii S. Aulchenko,Monique M.B. Breteler,André G. Uitterlinden,Albert Hofman,van Duijn Cm,P. Tikka-Kleemola,S. Vepsalainen,Susanne Lucae,Federica Tozzi,Pierandrea Muglia,Jeffrey C. Barrett,Jaakko Kaprio,Markus Färkkilä,Leena Peltonen,K. Stefansson,John-Anker Zwart,Ferrari,Jes Olesen,Mark J. Daly,Maija Wessman,van den Maagdenberg Am,Martin Dichgans,Christian Kubisch,Emmanouil T. Dermitzakis,Rune R. Frants,Aarno Palotie +64 more
TL;DR: This article identified the minor allele of rs1835740 on chromosome 8q22.1 to be associated with migraine (P = 5.38 x 10(-)(9), odds ratio = 1.23, 95% CI 1.150-1.324) in a genomewide association study of 2,731 migraine cases ascertained from three European headache clinics and 10,747 population-matched controls.
Genome-wide association study of migraine implicates a common susceptibility variant on 8q22.1
Verneri Anttila,Hreinn Stefansson,Mikko Kallela,U. Todt,Gisela M. Terwindt,Maria S Calafato,Dale R. Nyholt,Antigone S. Dimas,T. Freilinger,Bertram Müller-Myhsok,Ville Artto,Michael Inouye,Kirsi Alakurtti,Mari A. Kaunisto,Eija Hämäläinen,B. B. A. De Vries,AH Stam,Claudia M Weller,Axel Heinze,Katja Heinze-Kuhn,Ingrid Goebel,Guntram Borck,H. Gobel,Stacy Steinberg,Christiane Wolf,Asgeir Björnsson,Gudmundur H. Gudmundsson,M. Kirchmann,A. Hauge,Thomas Werge,Jean Schoenen,Johan G. Eriksson,Knut Hagen,Lars Jacob Stovner,Heinz Erich Wichmann,Thomas Meitinger,M. Alexander,Susanne Moebus,Stefan Schreiber,Y S Aulchenko,Monique M.B. Breteler,André G. Uitterlinden,Albert Hofman,C M van Duijn,P. Tikka-Kleemola,Salli Vepsäläinen,Susanne Lucae,Federica Tozzi,Pierandrea Muglia,Jeffrey C. Barrett,Jaakko Kaprio,Markus Färkkilä,Leena Peltonen,K. Stefansson,John-Anker Zwart,Michel D. Ferrari,Jes Olesen,Mark J. Daly,Maija Wessman,A.M.J.M. van den Maagdenberg,Martin Dichgans,Christian Kubisch,Emmanouil T. Dermitzakis,R.R. Frants,Aarno Palotie +64 more
TL;DR: To the knowledge, the data establish rs1835740 as the first genetic risk factor for migraine.
Journal ArticleDOI
CFH Y402H Confers Similar Risk of Soft Drusen and Both Forms of Advanced AMD
Kristinn P. Magnusson,Shan Duan,Shan Duan,Haraldur Sigurdsson,H. Petursson,Zhenglin Yang,Zhenglin Yang,Yu Zhao,Paul S. Bernstein,Jian Ge,Fridbert Jonasson,Einar Stefánsson,Gudleif Helgadottir,Norman A. Zabriskie,Thorlakur Jonsson,Asgeir Björnsson,Theodora Thorlacius,Palmi V. Jonsson,Gudmar Thorleifsson,Augustine Kong,Hreinn Stefansson,Kang Zhang,Kari Stefansson,Jeffrey R. Gulcher +23 more
TL;DR: The results suggest that CFH is a major risk factor of soft drusen, and additional genetic factors and/or environmental factors may be required for progression to advanced AMD.