V
Vianey Gonzalez-Villasana
Researcher at University of Texas MD Anderson Cancer Center
Publications - 23
Citations - 1193
Vianey Gonzalez-Villasana is an academic researcher from University of Texas MD Anderson Cancer Center. The author has contributed to research in topics: Cancer & Angiogenesis. The author has an hindex of 13, co-authored 18 publications receiving 958 citations. Previous affiliations of Vianey Gonzalez-Villasana include Universidad Autónoma de Nuevo León.
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Journal ArticleDOI
Tumour angiogenesis regulation by the miR-200 family
Chad V. Pecot,Rajesha Rupaimoole,Da Yang,Rehan Akbani,Cristina Ivan,Chunhua Lu,Sherry Y. Wu,Hee Dong Han,Maitri Y. Shah,Cristian Rodriguez-Aguayo,Justin Bottsford-Miller,Yuexin Liu,Sang Bae Kim,Anna K. Unruh,Vianey Gonzalez-Villasana,Huang L,Behrouz Zand,Myrthala Moreno-Smith,Lingegowda S. Mangala,Morgan Taylor,Heather J. Dalton,Vasudha Sehgal,Yunfei Wen,Yu Kang,Keith A. Baggerly,Ju Seog Lee,Prahlad T. Ram,Murali Ravoori,Vikas Kundra,Xinna Zhang,Rouba Ali-Fehmi,Ana M. Gonzalez-Angulo,Pierre P. Massion,George A. Calin,Gabriel Lopez-Berestein,Wei Zhang,Anil K. Sood +36 more
TL;DR: A difference in clinical outcome is demonstrated based on miR-200's role in blocking tumour angiogenesis, defined as its utility as a potential therapeutic agent in a cancer-dependent context.
Journal ArticleDOI
Combining anti-miR-155 with chemotherapy for the treatment of lung cancers.
Katrien Van Roosbroeck,Francesca Fanini,Tetsuro Setoyama,Cristina Ivan,Cristian Rodriguez-Aguayo,Enrique Fuentes-Mattei,Lianchun Xiao,Ivan Vannini,Roxana S. Redis,Lucilla D’Abundo,Lucilla D’Abundo,Xinna Zhang,Milena S. Nicoloso,Simona Rossi,Vianey Gonzalez-Villasana,Vianey Gonzalez-Villasana,Rajesha Rupaimoole,Manuela Ferracin,Fortunato Morabito,Antonino Neri,Peter P. Ruvolo,Vivian Ruvolo,Chad V. Pecot,Dino Amadori,Lynne V. Abruzzo,Steliana Calin,Xuemei Wang,M. James You,Alessandra Ferrajoli,Robert Z. Orlowski,William Plunkett,Tara M. Lichtenberg,Ramana V. Davuluri,Ioana Berindan-Neagoe,Ioana Berindan-Neagoe,Massimo Negrini,Ignacio I. Wistuba,Hagop M. Kantarjian,Anil K. Sood,Gabriel Lopez-Berestein,Michael J. Keating,Muller Fabbri,George A. Calin +42 more
TL;DR: The findings support the existence of an miR-155/TP53 feedback loop, which is involved in resistance to chemotherapy and which can be specifically targeted to overcome drug resistance, an important cause of cancer-related death.
Journal ArticleDOI
Enhancing chemotherapy response with sustained EphA2 silencing using multistage vector delivery
Haifa Shen,Haifa Shen,Cristian Rodriguez-Aguayo,Rong Xu,Vianey Gonzalez-Villasana,Junhua Mai,Yi Huang,Guodong Zhang,Xiaojing Guo,Litao Bai,Guoting Qin,Xiaoyong Deng,Qingpo Li,Donald R. Erm,Burcu Aslan,Xuewu Liu,Jason Sakamoto,Arturo Chavez-Reyes,Hee Dong Han,Anil K. Sood,Mauro Ferrari,Mauro Ferrari,Gabriel Lopez-Berestein +22 more
TL;DR: Treatment of SKOV3ip2 tumor mice with MSV/EphA2 biweekly for 6 weeks resulted in dose-dependent reduction of tumor weight and number of tumor nodules and inhibited growth of HeyA8-MDR tumors, which were otherwise resistant to docetaxel treatment.
Journal ArticleDOI
Therapeutic Silencing of KRAS using Systemically Delivered siRNAs
Chad V. Pecot,Sherry Y. Wu,Seth Bellister,Justyna Filant,Rajesha Rupaimoole,Takeshi Hisamatsu,Rajat Bhattacharya,Anshumaan Maharaj,Salma H. Azam,Cristian Rodriguez-Aguayo,Archana S. Nagaraja,Maria Pia Morelli,Kshipra M. Gharpure,Trent A. Waugh,Vianey Gonzalez-Villasana,Behrouz Zand,Heather J. Dalton,Scott Kopetz,Gabriel Lopez-Berestein,Lee M. Ellis,Anil K. Sood +20 more
TL;DR: A proof-of-concept approach to therapeutic KRAS targeting using nanoparticle delivery of siRNA is demonstrated, which highlights the potential translational impact of therapeutic RNA interference, which may have broad applications in oncology, especially for traditional “undruggable” targets.
Journal ArticleDOI
Adrenergic regulation of monocyte chemotactic protein 1 leads to enhanced macrophage recruitment and ovarian carcinoma growth.
Guillermo N. Armaiz-Pena,Vianey Gonzalez-Villasana,Archana S. Nagaraja,Cristian Rodriguez-Aguayo,Nouara C. Sadaoui,Rebecca L. Stone,Koji Matsuo,Heather J. Dalton,Rebecca A. Previs,Nicholas B. Jennings,Piotr L. Dorniak,Jean M. Hansen,Jesusa M.G. Arevalo,Steve W. Cole,Susan K. Lutgendorf,Anil K. Sood,Gabriel Lopez-Berestein +16 more
TL;DR: It is demonstrated that increased adrenergic signaling is associated with macrophage infiltration and mediated by tumor cell-derived MCP1 production, and in ovarian cancer patients, elevated peripheral blood monocytes and tumoral macrophages were associated with worse overall survival.