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Vicente Felipo

Researcher at Spanish National Research Council

Publications -  357
Citations -  13974

Vicente Felipo is an academic researcher from Spanish National Research Council. The author has contributed to research in topics: Hyperammonemia & Glutamate receptor. The author has an hindex of 60, co-authored 335 publications receiving 12520 citations. Previous affiliations of Vicente Felipo include Universidad Miguel Hernández de Elche & University of Seville.

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Patent

Steroid compound for use in the treatment of hepatic encephalopathy

TL;DR: In this paper, the steroidal compound 3-ethynyl-3- hydroxyandrostan-17-one oxime, or a pharmaceutically acceptable saltthereof,for usein treatment ofhepaticencephalopathy.
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Current state of knowledge of hepatic encephalopathy (part II): changes in brain white matter tracts integrity are associated with cognitive deficits in minimal hepatic encephalopathy.

TL;DR: MRI techniques have shown that the determination of BF in cerebellum can detect the presence of alterations in attention and coordination in cirrhotic patients earlier than the PHES (Bgold standard^ for the diagnosis of MHE), and alterations in the nitric oxide-cGMP pathway in patients with MHE are associated with impairment in BF in the cerebellums.
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A protein-free diet changes synaptosomal membrane fluidity and tyrosine and glutamate transport.

TL;DR: In synaptosomes from rats on protein-free diet the uptake of tyrosine was slightly reduced while that of glutamate was not affected, however, the exit of MSG was reduced.