V
Vicente Felipo
Researcher at Spanish National Research Council
Publications - 357
Citations - 13974
Vicente Felipo is an academic researcher from Spanish National Research Council. The author has contributed to research in topics: Hyperammonemia & Glutamate receptor. The author has an hindex of 60, co-authored 335 publications receiving 12520 citations. Previous affiliations of Vicente Felipo include Universidad Miguel Hernández de Elche & University of Seville.
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Journal ArticleDOI
Patients with Minimal Hepatic Encephalopathy Show Altered Thermal Sensitivity and Autonomic Function.
Dalia Rega,Mika Aiko,Nicolás Peñaranda,Amparo Urios,Juan-José Gallego,Carla Giménez-Garzó,Franc Casanova,Alessandra Fiorillo,Andrea Cabrera-Pastor,Teresa San-Miguel,Cristina Ipiens,Desamparados Escudero-García,Joan Tosca,Cristina Montón,María Pilar Ballester,José Ballester,Luis Aparicio,María-Pilar Ríos,Lucía Durbán,Amparo Mir,Elena Kosenko,Paula Cases,Vicente Felipo,Carmina Montoliu +23 more
TL;DR: In this paper, the relationship between minimal hepatic encephalopathy (MHE) and alterations in thermal, vibration, and/or heat pain sensitivity in 58 cirrhotic patients (38 without and 20 with MHE according to Psychometric Hepatic Encephalopathy Score) and 39 controls was assessed.
Journal ArticleDOI
Transport of AMPA receptors during long-term potentiation is impaired in rats with hepatic encephalopathy.
TL;DR: Long-term potentiation in hippocampus, considered the basis of some forms of learning and memory, is impaired in rats with portacaval shunt, and the mechanisms by which LTP is impaired are analyzed.
Journal ArticleDOI
Rats with minimal hepatic encephalopathy show reduced cGMP-dependent protein kinase activity in hypothalamus correlating with circadian rhythms alterations.
Vicente Felipo,Blanca Piedrafita,Juan A. Barios,Ana Agusti,Hanan Ahabrach,Maria Romero-Vives,Luis C. Barrio,Beatriz Rey,Jose M. Gaztelu,Marta Llansola +9 more
TL;DR: The aims of this work were to characterize the alterations in circadian rhythms in PCS rats and analyze the underlying mechanisms, and to analyze some mechanisms by which hypothalamus modulate circadian rhythms.
Journal ArticleDOI
Extracellular Vesicles From Hyperammonemic Rats Induce Neuroinflammation in Cerebellum of Normal Rats: Role of Increased TNFα Content
TL;DR: Ex vivo treatment of cerebellar slices from control rats with extracellular vesicles from hyperammonemic rats induce glial activation, neuroinflammation and enhance GABAergic neurotransmission, reproducing the effects induced byHyperammonemia in vivo, and key underlying mechanisms are identified.
Journal ArticleDOI
Presence of diadenosine polyphosphates in microdialysis samples from rat cerebellum in vivo: effect of mild hyperammonemia on their receptors
Javier Gualix,Rosa Gómez-Villafuertes,Jesús Pintor,Marta Llansola,Vicente Felipo,M. Teresa Miras-Portugal +5 more
TL;DR: The role of diadenosine polyphosphates as signaling molecules in the central nervous system is reinforced by the occurrence of Ap3A in the cerebellar microdyalisates and changes in the expression levels of their receptors and hydrolyzing enzymes in an animal model of moderate hyperammonemia.