V
Vicente Felipo
Researcher at Spanish National Research Council
Publications - 357
Citations - 13974
Vicente Felipo is an academic researcher from Spanish National Research Council. The author has contributed to research in topics: Hyperammonemia & Glutamate receptor. The author has an hindex of 60, co-authored 335 publications receiving 12520 citations. Previous affiliations of Vicente Felipo include Universidad Miguel Hernández de Elche & University of Seville.
Papers
More filters
Book ChapterDOI
Hyperammonemia Induces Brain Tubulin
TL;DR: It is found that hyperammonemia induces tubulin synthesis in brain, with maximum increases of tubulin content in hippocampus, septum and reticular formation while other areas such as locus coeruleus and mammillary nucleus are not affected at all.
Journal ArticleDOI
Precursors of mitochondrial proteins are degraded in the cytosol at different rates
Vicente Felipo,Santiago Grisolia +1 more
TL;DR: The stability of rat liver mitochondrial protein precursors in the cytosol was investigated using a post‐mitochondrial supernatant from rat liver and mitochondria added at different times to determine the amount and pattern of proteins incorporated.
Journal ArticleDOI
Actinomycin D decreases protein kinase C content and induces neuritogenesis in neuroblastoma cells
TL;DR: It is shown now that actinomycin D, a well known inhibitor of DNA synthesis, reduces selectively the content of protein kinase C and induces neuritogenesis in Neuro 2a cells in culture.
Journal ArticleDOI
Trialkylglycines: a new family of compounds with in vivo neuroprotective activity.
TL;DR: Two types of trialkylglycines have been found that significantly reduce the incidence of glutamate-induced neuronal death and might represent effective drugs for the treatment of neurodegeneration.
Journal ArticleDOI
Protein kinase C inhibitors, H7 and calphostin C, inhibit induction of DNA synthesis by cytosolic extracts of exponentially growing neuroblastoma cells in isolated nuclei
TL;DR: Cytoplasmic extracts from proliferating Neuro-2a cells contain a protein factor, ADR (activator of DNA replication) that induces DNA synthesis in isolated quiescent nuclei, but this activity can be generated after a brief exposure of cytosolic extracts to a membrane-enriched fraction derived from exponentially growing Neuro- 2a cells.