V
Vicente Felipo
Researcher at Spanish National Research Council
Publications - 357
Citations - 13974
Vicente Felipo is an academic researcher from Spanish National Research Council. The author has contributed to research in topics: Hyperammonemia & Glutamate receptor. The author has an hindex of 60, co-authored 335 publications receiving 12520 citations. Previous affiliations of Vicente Felipo include Universidad Miguel Hernández de Elche & University of Seville.
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Journal ArticleDOI
The Dual Role of the GABAA Receptor in Peripheral Inflammation and Neuroinflammation: A Study in Hyperammonemic Rats.
TL;DR: In this article, the GABAA antagonist bicuculline was administered daily for four weeks in control and hyperammonemic rats, and its effects on peripheral inflammation and on neuroinflammation as well as glutamate and GABA neurotransmission in the cerebellum were assessed.
Journal ArticleDOI
Rats with Mild Bile Duct Ligation Show Hepatic Encephalopathy with Cognitive and Motor Impairment in the Absence of Cirrhosis: Effects of Alcohol Ingestion
Carla Giménez-Garzó,Dounia Salhi,Amparo Urios,Amparo Ruiz-Sauri,Carmen Carda,Carmina Montoliu,Vicente Felipo +6 more
TL;DR: It is supported that the combination of certain levels of hyperammonemia and inflammation is enough to induce mild cognitive impairment, even in the absence of liver cirrhosis.
Journal ArticleDOI
Exit of proteins and fragments thereof from mitochondria is accelerated by the import of cytosolic synthesized proteins
TL;DR: These results strongly suggest that import of proteins from the cytosol into mitochondria influences the half-life of proteins in these organelles.
Journal ArticleDOI
Rats with minimal hepatic encephalopathy due to portacaval shunt show differential increase of translocator protein (18 kDa) binding in different brain areas, which is not affected by chronic MAP-kinase p38 inhibition
TL;DR: Assessment of TSPO-selective 3H-(R)-PK11195 binding to different brain areas indicates that SB239063-induced neuroinflammation reduction in PCS rats is not mediated by effects on T SPO, and enhanced TSPo expression is not always associated with cognitive or motor deficits.
Book ChapterDOI
Activation of NMDA Receptor Mediates the Toxicity of Ammonia and the Effects of Ammonia on the Microtubule-Associated Protein MAP-2
TL;DR: In Spain, nearly 12,000 people die every year by liver cirrhosis (-8,000) or other hepatic failures; this represents approximately 4% of the total number of deaths.