V
Vicente Felipo
Researcher at Spanish National Research Council
Publications - 357
Citations - 13974
Vicente Felipo is an academic researcher from Spanish National Research Council. The author has contributed to research in topics: Hyperammonemia & Glutamate receptor. The author has an hindex of 60, co-authored 335 publications receiving 12520 citations. Previous affiliations of Vicente Felipo include Universidad Miguel Hernández de Elche & University of Seville.
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Journal ArticleDOI
Modulation of NMDA receptor function by cyclic AMP in cerebellar neurones in culture
TL;DR: Results indicate that cAMP modulatesNMDA receptor in cerebellar neurones and may play a role in NMDA receptor modulation by other receptors.
Journal ArticleDOI
Prenatal Exposure of Rats to Ammonia Impairs NMDA Receptor Function and Affords Delayed Protection Against Ammonia Toxicity and Glutamate Neurotoxicity
TL;DR: Results indicate that exposure to ammonia during the prenatal and lactation periods results in long-lasting impairment of NMDA receptor function, which would be the reason for the delayed protection afforded by exposure to low ammonia levels against acute ammonia toxicity in animals and against glutamate and NMDA toxicity in neuronal cultures.
Journal ArticleDOI
An Inhibitor of Neuronal Exocytosis (DD04107) Displays Long-Lasting In Vivo Activity against Chronic Inflammatory and Neuropathic Pain
Berta Ponsati,Cristina Carreño,Verdad Curto-Reyes,Belén Valenzuela,Maria José Duart,Wim Van Den Nest,Omar Cauli,Beatriz Beltrán,Jimena Fernandez,Franco Borsini,Antonio Caprioli,Stefano Di Serio,Mario Veretchy,Ana Baamonde,Luis Menéndez,Francisco Barros,Pilar de la Peña,Ricardo Borges,Vicente Felipo,Rosa Planells-Cases,Antonio Ferrer-Montiel +20 more
TL;DR: These findings support the notion that neuronal exocytosis of receptors and neuronal algogens pivotally contribute to chronic inflammatory and neuropathic pain and imply a central role of peptidergic nociceptor sensitization to the pathogenesis of pain.
BookDOI
New trends in cancer for the 21st century
TL;DR: A large number of the patients in this study had at least one prior cancer diagnosis and the results confirmed the need for further exploration of these mechanisms and the role of “cell reprograming” in the diagnosis of cancer.
Journal ArticleDOI
The expression of nNOS, iNOS and nitrotyrosine is increased in the rat cerebral cortex in experimental hepatic encephalopathy.
TL;DR: Findings indicate that the induction of iNOS in pyramidal neurones and cortical astrocytes 6’months after PCA contributes to the generation of NT, and demonstrate the clear participation of NO in the pathogenic process of HE in this model.