V
Vincent M. Rotello
Researcher at University of Massachusetts Amherst
Publications - 797
Citations - 60364
Vincent M. Rotello is an academic researcher from University of Massachusetts Amherst. The author has contributed to research in topics: Nanoparticle & Colloidal gold. The author has an hindex of 108, co-authored 766 publications receiving 52473 citations. Previous affiliations of Vincent M. Rotello include Eindhoven University of Technology & Indiana University.
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Stability of gold nanoparticle-bound DNA toward biological, physical, and chemical agents.
TL;DR: The MMPC‐bound DNA was found to show enhanced cleavage upon exposure to chemically induced radicals, which may indicate that bound DNA is bent and wrapped on the surface of the cationic MMPC.
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Giant Vesicle Formation through Self-Assembly of Complementary Random Copolymers
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Acylsulfonamide-Functionalized Zwitterionic Gold Nanoparticles for Enhanced Cellular Uptake at Tumor pH
Tsukasa Mizuhara,Krishnendu Saha,Daniel F. Moyano,Chang Soo Kim,Bo Yan,Young Kwan Kim,Vincent M. Rotello +6 more
TL;DR: A nanoparticle design featuring pH-responsive alkoxyphenyl acylsulfonamide ligands is reported herein, which is a promising tool for tumor selective therapy because of its pH-controlled uptake and toxicity.
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Nanoparticle-Stabilized Capsules for the Treatment of Bacterial Biofilms.
Bradley Duncan,Xiaoning Li,Ryan F. Landis,Sung Tae Kim,Akash Gupta,Li-Sheng Wang,Rajesh Ramanathan,Rajesh Ramanathan,Rui Tang,Jeffrey A. Boerth,Vincent M. Rotello +10 more
TL;DR: The fabrication of a nanoparticle-stabilized capsule with a multicomponent core for the treatment of biofilms selectively promoted fibroblast proliferation in a mixed bacteria/mammalian cell system making them promising for wound healing applications.
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Towards an in vivo biologically inspired nanofactory
Philip R. LeDuc,Michael S. Wong,Placid M. Ferreira,Richard E. Groff,Kiryn Haslinger,Michael P. Koonce,Woo Y. Lee,J. Christopher Love,J. Andrew McCammon,Nancy A. Monteiro-Riviere,Vincent M. Rotello,Gary W. Rubloff,Robert M. Westervelt,Minami Yoda +13 more
TL;DR: It may, however, be possible to go even further and design 'pseudo-cell' nanofactories that work with molecules already in the body to fight disease.