V
Vincent Zoete
Researcher at Swiss Institute of Bioinformatics
Publications - 155
Citations - 20005
Vincent Zoete is an academic researcher from Swiss Institute of Bioinformatics. The author has contributed to research in topics: T-cell receptor & T cell. The author has an hindex of 43, co-authored 135 publications receiving 12342 citations. Previous affiliations of Vincent Zoete include Ludwig Institute for Cancer Research & University of Lausanne.
Papers
More filters
Journal ArticleDOI
Structure-based prediction of BRAF mutation classes using machine-learning approaches
F. Krebs,Christian Britschgi,Sylvain Pradervand,Rita Achermann,Petros Tsantoulis,Simon Haefliger,Andreas Wicki,Olivier Michielin,Vincent Zoete +8 more
TL;DR: In this paper , a new in-silico tool based on machine learning approaches was developed to predict the potential class of a missense variant of the BRAF kinase, which is more diverse and challenging to predict.
Journal ArticleDOI
Attracting Cavities 2.0: Improving the Flexibility and Robustness for Small-Molecule Docking
Ute F. Röhrig,Vincent Zoete +1 more
TL;DR: Zoete et al. as mentioned in this paper proposed the Attracting Cavities (AC) algorithm for molecular docking, which is a computational approach for predicting the most probable position of a ligand in the binding site of a target macromolecule.
Posted ContentDOI
Combination of NY-ESO-1-TCR-T-cells coengineered to secrete SiRPα decoys with anti-tumor antibodies to augment macrophage phagocytosis
E Stefanidis,Aikaterini Semilietof,Julien Pujol,Bili Seijo,Kirsten B.J. Scholten,Vincent Zoete,Olivier Michielin,Raphael Sandaltzopoulos,George Coukos,Melita Irving +9 more
TL;DR: In this paper , the authors developed a panel of affinity-enhanced T cell receptor (TCR)-engineered T cells (ACT) targeting the HLA-A2 restricted cancer-testis epitope NY-ESO-1157-165 (A2/NY) has yielded favorable clinical responses against a variety of cancers.
Journal ArticleDOI
Strong Enrichment of Aromatic and Sulfur-Containing Residues in Ligand-Protein Binding Sites.
TL;DR: Results show, for the first time, strong and highly correlated enrichments of aromatic and sulfur-containing residues, which play an important role in ligand binding and shape the nature of the chemical interactions.
Patent
Compounds for the treatment of oncovirus induced cancer and methods of use thereof
TL;DR: The pesent invention relates to compounds of formula (I) pharmaceutically acceptable salts, hydrates, solvates, or stereoisomers thereof and their use for the prevention and treatment of oncovirus induced cancer in a subject as mentioned in this paper.