V
Vivian F. Zhu
Researcher at University of Texas Health Science Center at Houston
Publications - 5
Citations - 523
Vivian F. Zhu is an academic researcher from University of Texas Health Science Center at Houston. The author has contributed to research in topics: Glioma & Pancreatic cancer. The author has an hindex of 5, co-authored 5 publications receiving 421 citations.
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Journal ArticleDOI
Deregulated signaling pathways in glioblastoma multiforme: molecular mechanisms and therapeutic targets.
TL;DR: The most common and important pathways that are highly mutated or deregulated in GBM are summarized and potential therapeutic strategies targeting these pathways are discussed.
Journal ArticleDOI
Understanding the role of cytokines in Glioblastoma Multiforme pathogenesis.
TL;DR: This review summarizes the current understanding of the functions of key cytokines on Glioblastoma Multiforme, and highlights potential therapeutic applications targeting these cytokines.
Journal ArticleDOI
A novel epigenetic CREB-miR-373 axis mediates ZIP4-induced pancreatic cancer growth.
Yuqing Zhang,Jingxuan Yang,Xiaobo Cui,Yong Chen,Vivian F. Zhu,John P. Hagan,Huamin Wang,Xianjun Yu,Sally E. Hodges,Jing（方靖） Fang,Paul J. Chiao,Craig D. Logsdon,William E. Fisher,F. Charles Brunicardi,F. Charles Brunicardi,Changyi Chen,Qizhi Yao,Martin E. Fernandez-Zapico,Min Li,Min Li +19 more
TL;DR: A novel mechanism where increased zinc mediated by the zinc importer ZIP4 transcriptionally induces miR‐373 in pancreatic cancer to promote tumour growth is reported, providing mechanistic insights explaining in part how a zinc transporter functions in cancer cells and may have broader implications as inappropriate regulation of intracellular zinc levels plays an important role in many other diseases.
Journal ArticleDOI
ZIP4 Promotes Muscle Wasting and Cachexia in Mice With Orthotopic Pancreatic Tumors by Stimulating RAB27B-Regulated Release of Extracellular Vesicles From Cancer Cells.
Jingxuan Yang,Jingxuan Yang,Zicheng Zhang,Yuqing Zhang,Xiaoling Ni,Xiaoling Ni,Guohua Zhang,Xiaobo Cui,Xiaobo Cui,Mingyang Liu,Can Xu,Qiang Zhang,Huiyun Zhu,Jie Yan,Vivian F. Zhu,Yusheng Luo,John P. Hagan,Zhao-Shen Li,Jing Fang,Jing Fang,Aminah Jatoi,Martin E. Fernandez-Zapico,Lei Zheng,Barish H. Edil,Michael S. Bronze,Courtney W. Houchen,Yi-Ping Li,Min Li +27 more
TL;DR: Mice with orthotopic tumors grown from pancreatic cancer cells with knockdown of ZIP4 survived longer and lost less body weight and muscle mass than mice with control tumors.
Journal ArticleDOI
ZIP4 is a novel molecular marker for glioma
Yi Lin,Yong Chen,Yongzhi Wang,Yongzhi Wang,Jingxuan Yang,Vivian F. Zhu,Yulun Liu,Xiaobo Cui,Leon Chen,Wei Yan,Tao Jiang,Georgene W. Hergenroeder,Stephen A. Fletcher,Jonathan M. Levine,Dong H. Kim,Nitin Tandon,Jay-Jiguang Zhu,Min Li +17 more
TL;DR: The results suggest that ZIP4 may serve as a potential diagnostic and prognostic marker for gliomas and is consistent across 2 independent cohorts (CGCA and REMBRANDT) and is partially validated by the third cohort (UT).