W
Wei Cao
Researcher at Baylor College of Medicine
Publications - 94
Citations - 8642
Wei Cao is an academic researcher from Baylor College of Medicine. The author has contributed to research in topics: Interferon & Chemistry. The author has an hindex of 29, co-authored 69 publications receiving 7732 citations. Previous affiliations of Wei Cao include Nanjing University of Science and Technology & University of Electronic Science and Technology of China.
Papers
More filters
Journal ArticleDOI
Plasmacytoid dendritic cells sense self-DNA coupled with antimicrobial peptide.
Roberto Lande,Josh Gregorio,Valeria Facchinetti,Bithi Chatterjee,Bithi Chatterjee,Yi Hong Wang,Bernhard Homey,Wei Cao,Yui-Hsi Wang,Bing Su,Frank O. Nestle,Tomasz Zal,Ira Mellman,Ira Mellman,Jens-Michael Schröder,Yong-Jun Liu,Michel Gilliet +16 more
TL;DR: The data uncover a fundamental role of an endogenous antimicrobial peptide in breaking innate tolerance to self-DNA and suggest that this pathway may drive autoimmunity in psoriasis.
Journal ArticleDOI
Plasmacytoid dendritic cells: sensing nucleic acids in viral infection and autoimmune diseases
TL;DR: Several pDC receptors negatively regulate type I IFN responses by pDCs during viral infection and for normal homeostasis, which normally prevents pDC responses to them.
Journal ArticleDOI
TSLP-activated dendritic cells induce an inflammatory T helper type 2 cell response through OX40 ligand
Tomoki Ito,Yui-Hsi Wang,Omar Duramad,Omar Duramad,Toshiyuki Hori,Guy Delespesse,Norihiko Watanabe,F. Xiao Feng Qin,Zhengbin Yao,Wei Cao,Yong-Jun Liu,Yong-Jun Liu +11 more
TL;DR: It is proposed that OX40L on TSLP-activated DCs triggers Th2 cell polarization in the absence of IL-12, and can switch IL-10–producing regulatory Th cell responses into TNF-α–producing inflammatory Th cell responds.
Journal ArticleDOI
Hassall's corpuscles instruct dendritic cells to induce CD4+CD25+ regulatory T cells in human thymus.
TL;DR: It is reported that human Hassall's corpuscles express thymic stromal lymphopoietin (TSLP), indicating a critical role in dendritic-cell-mediated secondary positive selection of medium-to-high affinity self-reactive T cells, leading to the generation of CD4+CD25+ regulatory T cells within the thymus.
Journal ArticleDOI
Identification of α-dystroglycan as a receptor for lymphocytic choriomeningitis virus and Lassa fever virus
Wei Cao,Michael D. Henry,Persephone Borrow,Hiroki Yamada,John H. Elder,Eugene V. Ravkov,Stuart T. Nichol,Richard W. Compans,Kevin P. Campbell,Michael B. A. Oldstone +9 more
TL;DR: A peripheral membrane protein that is interactive with lymphocytic choriomeningitis virus (LCMV) was purified from cells permissive to infection and determined to be alpha-dystroglycan (alpha-DG).