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Weijun Pan
Researcher at Chinese Academy of Sciences
Publications - 43
Citations - 3289
Weijun Pan is an academic researcher from Chinese Academy of Sciences. The author has contributed to research in topics: Wnt signaling pathway & Zebrafish. The author has an hindex of 20, co-authored 36 publications receiving 2872 citations. Previous affiliations of Weijun Pan include Shanghai Jiao Tong University & Laboratory of Molecular Biology.
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Journal ArticleDOI
Low-density lipoprotein receptor-related protein-5 binds to Axin and regulates the canonical Wnt signaling pathway.
Junhao Mao,Junhao Mao,Jiyong Wang,Bo Liu,Bo Liu,Weijun Pan,Gist H. Farr,Christopher Flynn,Huidong Yuan,Shinji Takada,David Kimelman,Lin Li,Dianqing Wu +12 more
TL;DR: It is concluded that the binding of Axin to LRP-5 is an important part of the Wnt signal transduction pathway, and the L RP-5 sequences involved in interactions with Axin are required for LEF-1 activation.
Journal ArticleDOI
GSK3: a multifaceted kinase in Wnt signaling
Dianqing Wu,Weijun Pan +1 more
TL;DR: The recent demonstration of GSK3 involvement in Wnt receptor phosphorylation illustrates the multifaceted roles that GSK2 plays in WNT-beta-catenin signaling and explanations, hypotheses, and models are offered to reconcile some of these observations.
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Sites of Regulated Phosphorylation that Control K-Cl Cotransporter Activity
Jesse Rinehart,Yelena Maksimova,Jessica E. Tanis,Kathryn L. Stone,Caleb A. Hodson,Junhui Zhang,Mary Risinger,Weijun Pan,Dianqing Wu,Christopher M. Colangelo,Biff Forbush,Clinton H. Joiner,Erol E. Gulcicek,Patrick G. Gallagher,Richard P. Lifton +14 more
TL;DR: Two sites in KCC3 that are rapidly dephosphorylated in hypotonic conditions in cultured cells and human red blood cells in parallel with increased transport activity are identified, providing insight into regulation of [Cl(-)](i) and have implications for control of cell volume and neuronal function.
Journal ArticleDOI
Vascular Development in the Zebrafish
TL;DR: The amenability of this model system for studying blood vessel development is discussed and contributions made by this system to the authors' understanding of vascular development are reviewed.
Journal ArticleDOI
Wnt3a-Mediated Formation of Phosphatidylinositol 4,5-Bisphosphate Regulates LRP6 Phosphorylation
Weijun Pan,Sun-Cheol Choi,He Wang,Yuanbo Qin,Laura A. Volpicelli-Daley,Laura E. Swan,Louise Lucast,Cynthia Khoo,Xiaowu Zhang,Lin Li,Charles S. Abrams,Sergei Y. Sokol,Dianqing Wu +12 more
TL;DR: A signaling mechanism for Wnt to regulate LRP6 phosphorylation is revealed, and phosphatidylinositol 4,5-bisphosphates are confirmed to be important for WNT signaling in Xenopus embryos.