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Xianyun Xie
Researcher at Washington University in St. Louis
Publications - 2
Citations - 3227
Xianyun Xie is an academic researcher from Washington University in St. Louis. The author has contributed to research in topics: Pittsburgh compound B & Alzheimer's disease. The author has an hindex of 2, co-authored 2 publications receiving 2738 citations.
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Journal ArticleDOI
Clinical and Biomarker Changes in Dominantly Inherited Alzheimer’s Disease
Randall J. Bateman,Chengjie Xiong,Tammie L.S. Benzinger,Anne M. Fagan,Alison Goate,Nick C. Fox,Daniel S. Marcus,Nigel J. Cairns,Xianyun Xie,Tyler Blazey,David M. Holtzman,Anna Santacruz,Virginia Buckles,Angela Oliver,Krista L. Moulder,Paul S. Aisen,Bernardino Ghetti,William E. Klunk,Eric McDade,Ralph N. Martins,Colin L. Masters,Richard Mayeux,John M. Ringman,Martin N. Rossor,Peter R. Schofield,Reisa A. Sperling,Stephen Salloway,John C. Morris +27 more
TL;DR: In this paper, a longitudinal study of 128 patients with Alzheimer's disease was conducted, where the authors used the participant's age at baseline assessment and the parent's age to calculate the estimated years from expected symptom onset (age of the participant minus parent's ages at symptom onset).
Journal ArticleDOI
Regional variability of imaging biomarkers in autosomal dominant Alzheimer’s disease
Tammie L.S. Benzinger,Tyler Blazey,Clifford R. Jack,Robert A. Koeppe,Yi Su,Chengjie Xiong,Marcus E. Raichle,Abraham Z. Snyder,Beau M. Ances,Randall J. Bateman,Nigel J. Cairns,Anne M. Fagan,Alison Goate,Daniel S. Marcus,Paul S. Aisen,Jon Christensen,Lindsay Ercole,Russ C. Hornbeck,Angela M. Farrar,Patricia Aldea,Mateusz S. Jasielec,Christopher J. Owen,Xianyun Xie,Richard Mayeux,Adam M. Brickman,Eric McDade,William E. Klunk,Chester A. Mathis,John M. Ringman,Paul M. Thompson,Bernardino Ghetti,Andrew J. Saykin,Reisa A. Sperling,Keith A. Johnson,Stephen Salloway,Stephen Correia,Peter R. Schofield,Peter R. Schofield,Colin L. Masters,Christopher C. Rowe,Victor L. Villemagne,Ralph N. Martins,Sebastien Ourselin,Martin N. Rossor,Nick C. Fox,David M. Cash,Michael W. Weiner,David M. Holtzman,Virginia Buckles,Krista L. Moulder,John C. Morris +50 more
TL;DR: An integrated whole-brain analysis of three major imaging techniques found that most gray-matter structures with amyloid plaques later have hypometabolism followed by atrophy, and a hypermetabolic phase was identified for some cortical regions, including the precuneus and posterior cingulate.