X
Xuelu Liu
Researcher at National Institutes of Health
Publications - 7
Citations - 2036
Xuelu Liu is an academic researcher from National Institutes of Health. The author has contributed to research in topics: Biology & Gene. The author has an hindex of 2, co-authored 2 publications receiving 1401 citations.
Papers
More filters
Journal ArticleDOI
Genetics and Pathogenesis of Diffuse Large B-Cell Lymphoma
Roland Schmitz,George E. Wright,Da-Wei Huang,Calvin A. Johnson,James D. Phelan,James Q. Wang,Sandrine Roulland,Monica Kasbekar,Ryan M. Young,Arthur L. Shaffer,Daniel J. Hodson,Wenming Xiao,Xin Yu,Yandan Yang,Hong Zhao,Weihong Xu,Xuelu Liu,Bin Zhou,Wei Du,Wing C. Chan,Elaine S. Jaffe,Randy D. Gascoyne,Joseph M. Connors,Elias Campo,Armando López-Guillermo,Andreas Rosenwald,German Ott,Jan Delabie,Lisa M. Rimsza,Kevin Tay Kuang Wei,Andrew D. Zelenetz,Andrew D. Zelenetz,John P. Leonard,John P. Leonard,Nancy L. Bartlett,Nancy L. Bartlett,Bao Tran,Jyoti Shetty,Yongmei Zhao,Dan R. Soppet,Stefania Pittaluga,Wyndham H. Wilson,Louis M. Staudt +42 more
TL;DR: Analysis of genetic pathways suggested that MCD and BN2 DLBCLs rely on “chronic active” B‐cell receptor signaling that is amenable to therapeutic inhibition, and an algorithm was developed and implemented to discover genetic subtypes based on the co‐occurrence of genetic alterations.
Journal ArticleDOI
Burkitt lymphoma pathogenesis and therapeutic targets from structural and functional genomics
Roland Schmitz,Ryan M. Young,Michele Ceribelli,Sameer Jhavar,Wenming Xiao,Meili Zhang,George E. Wright,Arthur L. Shaffer,Daniel J. Hodson,Eric Buras,Xuelu Liu,John Powell,Yandan Yang,Weihong Xu,Hong Zhao,Holger Kohlhammer,Andreas Rosenwald,Philip M. Kluin,Hans Konrad Müller-Hermelink,German Ott,Randy D. Gascoyne,Joseph M. Connors,Lisa M. Rimsza,Elias Campo,Elaine S. Jaffe,Jan Delabie,Erlend B. Smeland,Martin D. Ogwang,Steven J. Reynolds,Richard I. Fisher,Rita M. Braziel,Raymond R. Tubbs,James R. Cook,Dennis D. Weisenburger,Wing C. Chan,Stefania Pittaluga,Wyndham H. Wilson,Thomas A. Waldmann,Martin Rowe,Sam M. Mbulaiteye,Alan B. Rickinson,Louis M. Staudt +41 more
TL;DR: High-throughput RNA sequencing and RNA interference screening is used to discover essential regulatory pathways in Burkitt's lymphoma that cooperate with MYC, the defining oncogene of this cancer.
Journal ArticleDOI
Standards for the classification of pathogenicity of somatic variants in cancer (oncogenicity): Joint recommendations of Clinical Genome Resource (ClinGen), Cancer Genomics Consortium (CGC), and Variant Interpretation for Cancer Consortium (VICC).
Peter Horak,Malachi Griffith,Arpad Danos,Beth A. Pitel,Subhashree Madhavan,Xuelu Liu,Cynthia Chow,Heather E. Williams,Leigh C. Carmody,Lisa Barrow-Laing,Damian T. Rieke,Simon Kreutzfeldt,Albrecht Stenzinger,David Tamborero,Manuela Benary,Padma Sheila Rajagopal,Cristiane M. Ida,Harry Lesmana,Laveniya Satgunaseelan,Jason D. Merker,Michael Y. Tolstorukov,Paulo Vidal Campregher,Jeremy L. Warner,Shruti Rao,Maya Natesan,Haolin Shen,Jeffrey M. Venstrom,Somak Roy,Kayoko Tao,Rashmi Kanagal-Shamanna,Xinjie Xu,Deborah I. Ritter,Kymberleigh A. Pagel,Kilannin Krysiak,Adrian M. Dubuc,Yassmine Akkari,Xuan Li,Jennifer Lee,Ian King,Gordana Raca,Alex H. Wagner,Marylin M. Li,Sharon E. Plon,Shashikant Kulkarni,Obi L. Griffith,Debyani Chakravarty,Dmitriy Sonkin +46 more
TL;DR: In this paper , a standard operating procedure (SOP) for the classification of oncogenicity of somatic variants was developed to improve consistency in variants classification and has been validated on 94 variants in 10 common cancer-related genes.
Journal ArticleDOI
Standards for the classification of pathogenicity of somatic variants in cancer (oncogenicity): Joint recommendations of Clinical Genome Resource (ClinGen), Cancer Genomics Consortium (CGC), and Variant Interpretation for Cancer Consortium (VICC).
Peter Horak,Malachi Griffith,Arpad Danos,Beth A. Pitel,Subhashree Madhavan,Xuelu Liu,Cynthia Chow,Heather E. Williams,Leigh C. Carmody,Lisa Barrow-Laing,Damian T. Rieke,Simon Kreutzfeldt,Albrecht Stenzinger,David Tamborero,Manuela Benary,Padma Sheila Rajagopal,Cristiane M. Ida,Harry Lesmana,Laveniya Satgunaseelan,Jason D. Merker,Michael Y. Tolstorukov,Paulo Vidal Campregher,Jeremy L. Warner,Shruti Rao,Maya Natesan,H. Shen,Jeffrey M. Venstrom,Somak Roy,Kayoko Tao,Rashmi Kanagal-Shamanna,Xinjie Xu,Deborah I. Ritter,Kymberleigh A. Pagel,Kilannin Krysiak,Adrian M. Dubuc,Yassmine Akkari,Xuan Li,Jennifer Lee,Ian King,Gordana Raca,Alex H. Wagner,Marylin M. Li,Sharon E. Plon,Shashikant Kulkarni,Obi L. Griffith,Debyani Chakravarty,Dmitriy Sonkin +46 more
TL;DR: A comprehensive SOP has been developed to improve consistency in somatic variant classification and has been validated on 94 somatic variants in 10 common cancer-related genes.
Journal ArticleDOI
20. A unified framework for gene fusion representation
Alex H. Wagner,Yassmine Akkari,Jeremy A. Arbesfeld,Michael Baudis,Linda B. Baughn,Julia Bridge,Paulo Vidal Campregher,M. Ceccarelli,Karl J. Clark,Robert R. Freimuth,Peter Horak,Kori Kuzma,Kristy Lee,Jennifer Lee,Marilyn Li,Jie-yu Liu,Xuelu Liu,Scott P. Myrand,Angshumoy Roy,Jason Saliba,Laveniya Satgunaseelan,Andrea Sboner,Dmitriy Sonkin,Albrecht Stenzinger,James Stevenson,Anna Tańska,Gokce Altay Toruner,Karen Tsuchiya,Ioannis A. Vlachos,Xinjie Xu,Liying Zhang,Ying Zou,Gordana Raca +32 more