Y
Yasnory F. Sasaki
Researcher at National Institute of Advanced Industrial Science and Technology
Publications - 17
Citations - 2551
Yasnory F. Sasaki is an academic researcher from National Institute of Advanced Industrial Science and Technology. The author has contributed to research in topics: Paraspeckle & Olfactory bulb. The author has an hindex of 15, co-authored 17 publications receiving 2369 citations. Previous affiliations of Yasnory F. Sasaki include Harvard University & Sanford-Burnham Institute for Medical Research.
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Journal ArticleDOI
Increased NMDA current and spine density in mice lacking the NMDA receptor subunit NR3A.
Saumya Das,Yasnory F. Sasaki,Thomas Rothe,Louis S. Premkumar,Mari A. Takasu,James E. Crandall,Pieter Dikkes,David A. Conner,P.V. Rayudu,Wing S Cheung,H.-S. Vincent Chen,Stuart A. Lipton,Stuart A. Lipton,Nobuki Nakanishi +13 more
TL;DR: The characterization of a regulatory NMDAR subunit, NR3A, is reported, which is expressed primarily during brain development and suggested to be involved in the development of synaptic elements by modulating N MDAR activity.
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MENε/β noncoding RNAs are essential for structural integrity of nuclear paraspeckles
TL;DR: A model for nuclear paraspeckle body organization is postulate where specific ncRNAs and RNA-binding proteins cooperate to maintain and, presumably, establish the structure.
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Alternative 3'-end processing of long noncoding RNA initiates construction of nuclear paraspeckles.
Takao Naganuma,Shinichi Nakagawa,Akie Tanigawa,Yasnory F. Sasaki,Naoki Goshima,Tetsuro Hirose +5 more
TL;DR: In vitro binding assays showed that HNRNPK competed with CPSF6 for binding to NUDT21, which was the underlying mechanism to arrest CFIm binding by HNR NPK, which led to the preferential accumulation of NEAT1_2 and initiated paraspeckle construction with multiple PSPs.
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Synchronized oscillatory discharges of mitral/tufted cells with different molecular receptive ranges in the rabbit olfactory bulb.
TL;DR: The results suggest that the neuronal circuit in the olfactory bulb causes synchronized spike discharging of specific pairs of mitral/tufted cells associated with different glomeruli and the synchronization of odor-evoked spike discharges may contribute to the temporal binding of signals derived from different types of odorant receptor.
Journal ArticleDOI
Characterization and comparison of the NR3A subunit of the NMDA receptor in recombinant systems and primary cortical neurons.
Yasnory F. Sasaki,Yasnory F. Sasaki,Thomas Rothe,Thomas Rothe,Louis S. Premkumar,Saumya Das,Jiankun Cui,Maria Talantova,Hon-Kit Wong,Xiandi Gong,Shing Fai Chan,Dongxian Zhang,Dongxian Zhang,Dongxian Zhang,Nobuki Nakanishi,Nobuki Nakanishi,Nikolaus J. Sucher,Stuart A. Lipton,Stuart A. Lipton,Stuart A. Lipton +19 more
TL;DR: It is shown that recombinantly expressedNR3A in COS cells is biochemically associated with both NR1 and NR2 subunits, and whole cell NMDA-evoked currents are larger in NR3A-deficient mice compared with wild-type mice, and this effect follows a developmental pattern similar to that of NR3B protein expression on Western blots.