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Yi Yan Yang
Researcher at Agency for Science, Technology and Research
Publications - 374
Citations - 22011
Yi Yan Yang is an academic researcher from Agency for Science, Technology and Research. The author has contributed to research in topics: Micelle & Antimicrobial. The author has an hindex of 75, co-authored 358 publications receiving 19328 citations. Previous affiliations of Yi Yan Yang include National University of Singapore & Imperial College London.
Papers
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Journal ArticleDOI
Drug-free neutrally charged polypeptide nanoparticles as anticancer agents.
Shengcai Yang,Jia Hui. Leong,Yanming Wang,Rachel Hui Zhen Sim,K. Tan,Yau Hong Chua,Nathanael Tak Thye Tan,Ashlynn L. Z. Lee,Joyce Mei Hui. Tay,Yi Yan Yang +9 more
TL;DR: In this paper , a nanoparticulate delivery system self-assembled from a negatively charged pH-sensitive polypeptide poly(ethylene glycol)-b-poly(ʟ-lysine)-graft-cyclohexene-1,2-dicarboxylic anhydride via electrostatic interaction.
Patent
Antimicrobial surface modified silicone rubber and methods of preparation thereof
TL;DR: An antimicrobial silicone rubber as discussed by the authors comprises a silicone rubber substrate, a catechol layer bound to a surface of the substrate, and an antimicrobial layer disposed on the catecholic layer.
Patent
Vitamin functionalized gel-forming block copolymers for biomedical applications
TL;DR: Gel-forming block copolymers were used to prepare various biodegradable and/or biocompatible hydrogel and organogel drug compositions, in particular antimicrobial and anti-tumor drug compositions as mentioned in this paper.
Patent
Antimicrobial guanidinium macromolecules with bacteria targeting moieties
TL;DR: In this article, an antimicrobial guanidinium macromolecule with one or more targeting moieties for selectively targeting bacteria is provided. But the method is not described.
Journal ArticleDOI
Branched α-helical peptides enhanced antitumor efficacy and selectivity
Xiaowei Wang,Yiran Zheng,Chang Bao,Guansheng Zhong,Shaoqiong Liu,Nikken Wiradharma,Weimin Fan,Yi Yan Yang,Xiaojia Wang,Yuan Huang +9 more
TL;DR: The in vivo study in mice bearing breast tumors showed that branched peptides could be retained at the tumour sites after intratumoral injection and significantly reduced tumor growth while exhibiting minimal toxicity on main organs, indicating that the 4-arm brANChed peptide is a promising candidate for anticancer therapy.