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Yi Yan Yang
Researcher at Agency for Science, Technology and Research
Publications - 374
Citations - 22011
Yi Yan Yang is an academic researcher from Agency for Science, Technology and Research. The author has contributed to research in topics: Micelle & Antimicrobial. The author has an hindex of 75, co-authored 358 publications receiving 19328 citations. Previous affiliations of Yi Yan Yang include National University of Singapore & Imperial College London.
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Advanced Materials for Co‐Delivery of Drugs and Genes in Cancer Therapy
TL;DR: Key advances in drug and gene delivery are summarized with focus on the development of polymers, peptides, liposomes and inorganic materials as nanocarriers for co‐delivery of small molecular drugs and macromolecular genes or proteins.
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Chitosan-g-PEG/DNA complexes deliver gene to the rat liver via intrabiliary and intraportal infusions.
TL;DR: This study has examined the possibility of using polyethylene glycol (PEG)‐grafted chitosan/DNA complexes to deliver genes to the liver through bile duct and portal vein infusions.
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Thermosensitive Poly(N-isopropylacrylamide-co-acrylic acid) Hydrogels with Expanded Network Structures and Improved Oscillating Swelling−Deswelling Properties
TL;DR: In this article, a P(NIPAAm-co-AAc) hydrogel with rapid temperature sensitivity and improved oscillatory properties over small temperature cycles around the physiologic temperature of 37 °C was synthesized.
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Synthetic hydrogels for controlled stem cell differentiation
TL;DR: Recent advances in the synthesis and modification of PEG hydrogels will be presented, along with important physicochemical considerations in the design of these hydrogel to better mimic the stem cell microenvironment and direct stem cell differentiation.
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Ovarian cancer immunotherapy using PD-L1 siRNA targeted delivery from folic acid-functionalized polyethylenimine: strategies to enhance T cell killing.
Pei Yun Teo,Chuan Yang,Lynsey M. Whilding,Lynsey M. Whilding,Ana C. Parente-Pereira,John Maher,Andrew J.T. George,James L. Hedrick,Yi Yan Yang,Sadaf Ghaem-Maghami +9 more
TL;DR: These findings are the first to demonstrate that PD‐L1 knockdown in EOC cells, via siRNA/FA‐targeted delivery, are able to sensitize cancer cells to T cell killing.