Yi Yan Yang

TL;DR: Biodistribution and anti‐tumor efficacy studies performed in BT474 tumor‐bearing mice show that single subcutaneous injection of Herceptin‐loaded hydrogel at a site close to the tumor enhances the retention of the antibody within the tumor.

TL;DR: Findings from the synthesis of well-defined model PEGylated poly(dimethylaminoethyl methacrylate) based cationic polymers composed of different PEG architecture with controlled PEG and nitrogen content via reversible addition-fragmentation chain transfer (RAFT) polymerization provide important insights into the effect of P EGylation nature on gene expression.

TL;DR: This review article discusses the design strategies of polymersomes developed for enhanced transport and efficacy of imaging probes and therapeutic drugs, and focuses on overviewing technologies to regulate the size, structure, shape, surface activity, and stimuli‐ responsiveness ofpolymersomes.

TL;DR: Computational modeling demonstrated how subtle core changes could directly alter urea stacking motifs manifesting in unique multidirectional hydrogen-bond networks despite the vast majority of material consisting of poly(lactide) (interior block) and cationic polycarbonates (exterior block).

TL;DR: This study devise a strategy for the development of highly efficacious and skin compatible yet inexpensive water-soluble macromolecular antimicrobial polyionenes by employing a catalyst-free, polyaddition polymerization using commercially available monomers.