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Yi Yan Yang
Researcher at Agency for Science, Technology and Research
Publications - 374
Citations - 22011
Yi Yan Yang is an academic researcher from Agency for Science, Technology and Research. The author has contributed to research in topics: Micelle & Antimicrobial. The author has an hindex of 75, co-authored 358 publications receiving 19328 citations. Previous affiliations of Yi Yan Yang include National University of Singapore & Imperial College London.
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Efficient intracellular delivery of functional proteins using cationic polymer core/shell nanoparticles
TL;DR: The results obtained from cytotoxicity tests show that lectin A-chain delivered by the nanoparticles was significantly more toxic against MDA-MB-231, HeLa, HepG2 and 4T1 cell lines when compared to BioPorter.
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POE-PEG-POE triblock copolymeric microspheres containing protein. I. Preparation and characterization.
TL;DR: The fundamentals of the fabrication and characterization of POE-PEG-POE microspheres containing bovine serum albumin (BSA) were prepared using a double-emulsion (water-in-oil- in-water) process and SEM pictures show that an increase in PEG content results in micro Spheres with a denser cross-section because of a more stable first emulsion and better affinity between the copolymer and water.
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Block copolymer mixtures as antimicrobial hydrogels for biofilm eradication
TL;DR: High degree of synergistic antimicrobial effects was also observed through the co-delivery of antimicrobial polycarbonates with a conventionally-used antifungal agent, fluconazole, and these hydrogels displayed excellent compatibility with human dermal fibroblasts with cell viability >80% after treatment with hydrogel loaded with cationic polymers and/or flu Conazole at minimum biocidal concentrations (MBC).
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Room temperature synthesis of non-isocyanate polyurethanes (NIPUs) using highly reactive N-substituted 8-membered cyclic carbonates
Alexander Y. Yuen,Amaury Bossion,Amaury Bossion,Enrique Gómez-Bengoa,Fernando Ruipérez,Mehmet Isik,James L. Hedrick,David Mecerreyes,David Mecerreyes,Yi Yan Yang,Haritz Sardon +10 more
TL;DR: In this article, a (bis) N-substituted 8-membered cyclic carbonate was used for the synthesis of polyurethane polyureths.
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Dual pH-Responsive Shell-Cleavable Polycarbonate Micellar Nanoparticles for in Vivo Anticancer Drug Delivery.
Shaoqiong Liu,Robert J. Ono,Chuan Yang,Shujun Gao,Jordan Yong Ming Tan,James L. Hedrick,Yi Yan Yang +6 more
TL;DR: Dual pH-responsive bortezomib-polymer conjugates (BTZ-PC) self-assemble into micellar nanoparticles of small size (<110 nm) with narrow size distribution and high drug loading capacity and are a potentially promising carrier for BTZ delivery.