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Yi Yan Yang
Researcher at Agency for Science, Technology and Research
Publications - 374
Citations - 22011
Yi Yan Yang is an academic researcher from Agency for Science, Technology and Research. The author has contributed to research in topics: Micelle & Antimicrobial. The author has an hindex of 75, co-authored 358 publications receiving 19328 citations. Previous affiliations of Yi Yan Yang include National University of Singapore & Imperial College London.
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The potent antimicrobial properties of cell penetrating peptide-conjugated silver nanoparticles with excellent selectivity for Gram-positive bacteria over erythrocytes
TL;DR: The cell penetrating peptide catalyzed formation of antimicrobial silver nanoparticles in N,N-dimethylformamide demonstrated a distinctly enhanced biocidal effect toward bacteria and pathogenic yeast, while minimizing the toxic effects.
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Polymeric micelles anchored with TAT for delivery of antibiotics across the blood-brain barrier.
Lihong Liu,Subbu S. Venkatraman,Yi Yan Yang,Kun Guo,Jia Lu,Bei Ping He,Shabbir Moochhala,Lijing Kan +7 more
TL;DR: Polymeric micelles self-assembled from cholesterol-conjugated poly(ethylene glycol) (PEG) and anchored with transcriptional activator TAT peptide (TAT-PEG-b-Col) were fabricated for delivery of antibiotics across the blood-brain barrier (BBB) and proved to cross the BBB and enter the brain.
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Using mixed solvent to synthesize temperature sensitive poly(N-isopropylacrylamide) gel with rapid dynamics properties.
TL;DR: A novel technique to prepare a fast response poly(N-isopropylacrylamide) (PNIPA) gel is proposed by using water/acetone as a mixed solvent during the polymerization/crosslinking reaction, which leads to an expanded structure and a large swelling ratio of the gel in water at room temperature.
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Core–Shell–Corona Micelle Stabilized by Reversible Cross-Linkage for Intracellular Drug Delivery
TL;DR: With enhanced stability during circulation after administration, and accelerated intracellular drug release at the target site, the biocompatible and biodegradable shell-cross-linked polymeric micelle is promising as a drug vehicle for cancer chemotherapy.