Y
Ying Huang
Researcher at Fred Hutchinson Cancer Research Center
Publications - 157
Citations - 5311
Ying Huang is an academic researcher from Fred Hutchinson Cancer Research Center. The author has contributed to research in topics: Medicine & Population. The author has an hindex of 35, co-authored 132 publications receiving 4496 citations. Previous affiliations of Ying Huang include Iowa State University & Columbia University.
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Journal ArticleDOI
Antibody-Dependent Cellular Cytotoxicity-Mediating Antibodies from an HIV-1 Vaccine Efficacy Trial Target Multiple Epitopes and Preferentially Use the VH1 Gene Family
Mattia Bonsignori,Justin Pollara,M. Anthony Moody,Michael D. Alpert,Xi Chen,Kwan-Ki Hwang,Peter B. Gilbert,Ying Huang,Thaddeus C. Gurley,Daniel M. Kozink,Dawn J. Marshall,John F. Whitesides,Chun-Yen Tsao,Jaranit Kaewkungwal,Sorachai Nitayaphan,Punnee Pitisuttithum,Supachai Rerks-Ngarm,Jerome H. Kim,Nelson L. Michael,Georgia D. Tomaras,David C. Montefiori,George K. Lewis,Anthony L. DeVico,David T. Evans,Guido Ferrari,Hua-Xin Liao,Barton F. Haynes +26 more
TL;DR: The polyclonality and low mutation frequency of these VH1 antibodies reveal fundamental differences in the regulation and maturation of these ADCC-mediating responses compared to VH2 bNAbs, which recently described for CD4-binding site broadly neutralizing antibodies.
Journal ArticleDOI
Evaluation and Comparison of Food Records, Recalls, and Frequencies for Energy and Protein Assessment by Using Recovery Biomarkers
Ross L. Prentice,Yasmin Mossavar-Rahmani,Ying Huang,Linda Van Horn,Shirley A.A. Beresford,Bette J. Caan,Lesley F. Tinker,Dale A. Schoeller,Sheila Bingham,Charles B. Eaton,Cynthia A. Thomson,Karen C. Johnson,Judy Ockene,Gloria E. Sarto,Gerardo Heiss,Marian L. Neuhouser +15 more
TL;DR: Through comparison with biomarkers, the food record is shown to provide a stronger estimate of energy and protein than does the food frequency questionnaire, with 24-hour recalls mostly intermediate.
Journal ArticleDOI
Protein intake and incident frailty in the Women's Health Initiative observational study.
Jeannette M. Beasley,Andrea Z. LaCroix,Marian L. Neuhouser,Ying Huang,Lesley F. Tinker,Nancy Woods,Yvonne L. Michael,J. David Curb,Ross L. Prentice +8 more
TL;DR: Beasley et al. as discussed by the authors evaluated the association between protein intake and incident frailty and found that higher protein consumption, as a fraction of energy, is associated with a strong, independent, dose-responsive lower risk of incident dementia in older women.
Journal ArticleDOI
Magnitude and Breadth of the Neutralizing Antibody Response in the RV144 and Vax003 HIV-1 Vaccine Efficacy Trials
David C. Montefiori,Chitraporn Karnasuta,Ying Huang,Hasan Ahmed,Peter B. Gilbert,Mark de Souza,Robert McLinden,Sodsai Tovanabutra,Agnes Laurence-Chenine,Eric Sanders-Buell,M. Anthony Moody,Mattia Bonsignori,Christina Ochsenbauer,John C. Kappes,Haili Tang,Kelli Greene,Hongmei Gao,Celia C. LaBranche,Charla Andrews,Victoria R. Polonis,Supachai Rerks-Ngarm,Punnee Pitisuttithum,Sorachai Nitayaphan,Jaranit Kaewkungwal,Steve Self,Phillip W. Berman,Donald P. Francis,Faruk Sinangil,Carter Lee,Jim Tartaglia,Merlin L. Robb,Barton F. Haynes,Nelson L. Michael,Jerome H. Kim +33 more
TL;DR: The results suggest either that weak neutralizing antibody responses can be partially protective against HIV-1 in low-risk heterosexual populations or that the modest efficacy seen in RV144 was mediated by other immune responses, either alone or in combination with neutralizing antibodies.
Journal ArticleDOI
Integrating the Predictiveness of a Marker with Its Performance as a Classifier
Margaret S. Pepe,Margaret S. Pepe,Ziding Feng,Ying Huang,Gary Longton,Ross L. Prentice,Ian M. Thompson,Yingye Zheng +7 more
TL;DR: The authors propose that the predictiveness and classification performance of a marker, displayed together in an integrated plot, provide a comprehensive and cohesive assessment of a risk marker or model.