Y
Yongxia Shi
Publications - 35
Citations - 2526
Yongxia Shi is an academic researcher. The author has contributed to research in topics: Virus & Medicine. The author has an hindex of 8, co-authored 27 publications receiving 1724 citations.
Papers
More filters
Journal ArticleDOI
Identifying SARS-CoV-2-related coronaviruses in Malayan pangolins.
Tommy Tsan-Yuk Lam,Na Jia,Ya-Wei Zhang,Marcus Ho-Hin Shum,Jia-Fu Jiang,Hongbo Zhu,Yigang Tong,Yongxia Shi,Xue-Bing Ni,Yunshi Liao,Wen-Juan Li,Bao-Gui Jiang,Wei Wei,Ting-Ting Yuan,Kui Zheng,Xiao-Ming Cui,Jie Li,Guangqian Pei,Xin Qiang,William Yiu-Man Cheung,Lian-Feng Li,Fang-Fang Sun,Si Qin,Jicheng Huang,Gabriel M. Leung,Edward C. Holmes,Yan-Ling Hu,Yi Guan,Wu-Chun Cao +28 more
TL;DR: The discovery of multiple lineages of pangolin coronavirus and their similarity to SARS-CoV-2 suggests that pangolins should be considered as possible hosts in the emergence of new coronaviruses and should be removed from wet markets to prevent zoonotic transmission.
Journal ArticleDOI
Generation of a Broadly Useful Model for COVID-19 Pathogenesis, Vaccination, and Treatment.
Jing Sun,Zhen Zhuang,Jian Zheng,Kun Li,Roy Lok-Yin Wong,Donglan Liu,Jicheng Huang,Jiangping He,Airu Zhu,Jingxian Zhao,Xiaobo Li,Yin Xi,Rongchang Chen,Abeer N. Alshukairi,Zhao Chen,Zhaoyong Zhang,Chunke Chen,Xiaofang Huang,Fang Li,Xiaomin Lai,Dingbin Chen,Liyan Wen,Jianfen Zhuo,Yanjun Zhang,Yanqun Wang,Shuxiang Huang,Jun Dai,Yongxia Shi,Kui Zheng,Mariah R. Leidinger,Jiekai Chen,Yimin Li,Nanshan Zhong,David K. Meyerholz,Paul B. McCray,Stanley Perlman,Jincun Zhao +36 more
TL;DR: A murine model of broad and immediate utility is described to investigate COVID-19 pathogenesis, and to evaluate new therapies and vaccines.
Journal ArticleDOI
Isolation of infectious SARS-CoV-2 from urine of a COVID-19 patient.
Jing Sun,Airu Zhu,Heying Li,Kui Zheng,Zhen Zhuang,Zhao Chen,Yongxia Shi,Zhaoyong Zhang,Si bei Chen,Xuesong Liu,Jun Dai,Xiaobo Li,Shuxiang Huang,Xiaofang Huang,Ling Luo,Liyan Wen,Jianfen Zhuo,Yuming Li,Yanqun Wang,Lu Zhang,Yanjun Zhang,Fang Li,Liqiang Feng,Xinwen Chen,Nanshan Zhong,Zifeng Yang,Jicheng Huang,Jincun Zhao,Yimin Li +28 more
TL;DR: In conclusion, infectious SARS-CoV-2 was successfully isolated from urine of a COVID-19 patient and could infect new susceptible cells and was recognized by its’ own patient sera.
Journal ArticleDOI
Mapping and role of T cell response in SARS-CoV-2-infected mice.
Zhen Zhuang,Xiaomin Lai,Jing Sun,Zhao Chen,Zhaoyong Zhang,Jun Dai,Donglan Liu,Yuming Li,Fang Li,Yanqun Wang,Airu Zhu,J Wang,Wenhui Yang,Jicheng Huang,Xiaobo Li,Lingfei Hu,Liyan Wen,Jianfen Zhuo,Yanjun Zhang,Dingbin Chen,Suxiang Li,Shuxiang Huang,Yongxia Shi,Kui Zheng,Nanshan Zhong,Jingxian Zhao,Dongsheng Zhou,Jincun Zhao +27 more
TL;DR: In this paper, the authors used mice sensitized for infection with SARS-CoV-2 by transduction with an adenovirus expressing the human receptor (Ad5-hACE2).
Journal ArticleDOI
Liu Shen capsule shows antiviral and anti-inflammatory abilities against novel coronavirus SARS-CoV-2 via suppression of NF-κB signaling pathway.
Qinhai Ma,Weiqi Pan,Run-Feng Li,Bin Liu,Chufang Li,Yuqi Xie,Zhoulang Wang,Jin Zhao,Haiming Jiang,Jicheng Huang,Yongxia Shi,Jun Dai,Kui Zheng,Xiaobo Li,Zifeng Yang +14 more
TL;DR: Findings indicate that LS could inhibit SARS-CoV-2 virus infection via downregulating the expression of inflammatory cytokines induced virus and regulating the activity of NF-κB/MAPK signaling pathway in vitro, making its promising candidate treatment for controlling COVID-19 disease.