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Yoshiki Yamaguchi
Researcher at Tohoku Pharmaceutical University
Publications - 270
Citations - 7268
Yoshiki Yamaguchi is an academic researcher from Tohoku Pharmaceutical University. The author has contributed to research in topics: Glycan & Glycosylation. The author has an hindex of 41, co-authored 247 publications receiving 6186 citations. Previous affiliations of Yoshiki Yamaguchi include University of Tokyo & Max Planck Society.
Papers
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Journal ArticleDOI
Characterization of Autoantibodies against the E1α Subunit of Branched-Chain 2-Oxoacid Dehydrogenase in Patients with Primary Biliary Cirrhosis
TL;DR: Findings suggest that the E1α subunit as part of the native BCOADC complex is an immunogen, and that determinant spreading is involved in the pathogenesis of AMA production.
Journal ArticleDOI
Simple Gd3+-Neu5NAc complexation results in NMR chemical shift asymmetries of structurally equivalent complex-type N-glycan branches
Konstantin S. Usachev,Yoshiki Yamaguchi,Masayuki Takamatsu,Nataliya Pavlova,Vladimir V. Klochkov,Almira Kurbangalieva,Takefumi Murase,Taiji Shimoda,Katsunori Tanaka +8 more
TL;DR: This Communication proposes a quite simple but previously overlooked approach for conveniently analyzing, assigning, and extracting sialic acid-containing N-glycan structures using high-resolution NMR spectroscopy without pre-installing metal chelators.
Patent
Protein-including spherical transition metal complex and method for producing the same
TL;DR: In this paper, a protein-including spherical transition metal complex with a hollow shell composed of transition metal atoms and bidentate organic ligands is presented, in which one of the bidentates is bonded through a connecting group to a protein and the protein is formed to be oriented in the hollow shell inside.
Journal ArticleDOI
NMR assignments of the N -glycans of the Fc fragment of mouse immunoglobulin G2b glycoprotein
Saeko Yanaka,Saeko Yanaka,Yoshiki Yamaguchi,Takeshi Takizawa,Yohei Miyanoiri,Rina Yogo,Rina Yogo,Ichio Shimada,Koichi Kato,Koichi Kato +9 more
TL;DR: Based on spectral assignments of the N-glycans as well as polypeptide backbones of Fc, this paper showed that degalactosylation structurally perturbed the Fc region through rearrangement of glycan-protein interactions.