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Yoshiki Yamaguchi
Researcher at Tohoku Pharmaceutical University
Publications - 270
Citations - 7268
Yoshiki Yamaguchi is an academic researcher from Tohoku Pharmaceutical University. The author has contributed to research in topics: Glycan & Glycosylation. The author has an hindex of 41, co-authored 247 publications receiving 6186 citations. Previous affiliations of Yoshiki Yamaguchi include University of Tokyo & Max Planck Society.
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Journal ArticleDOI
920 MHz ultra-high field NMR approaches to structural glycobiology
Koichi Kato,Hiroaki Sasakawa,Hiroaki Sasakawa,Yukiko Kamiya,Maho Utsumi,Maho Utsumi,Michiko Nakano,Noriko Takahashi,Noriko Takahashi,Yoshiki Yamaguchi +9 more
TL;DR: It is demonstrated that ultra-high fields offer not only increases in sensitivity and chemical shift dispersion but also potential benefits for providing unique information on chemical exchange and relaxation, by displaying NMR spectral data of oligosaccharide, glycoprotein, and glycolipid systems recorded at a 21.6 T magnetic field.
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High-Sensitivity and Low-Toxicity Fucose Probe for Glycan Imaging and Biomarker Discovery.
Yasuhiko Kizuka,Sho Funayama,Hidehiko Shogomori,Miyako Nakano,Kazuki Nakajima,Kazuki Nakajima,Ritsuko Oka,Shinobu Kitazume,Yoshiki Yamaguchi,Masahiro Sano,Hiroaki Korekane,Tsui-Ling Hsu,Hsiu Yu Lee,Chi-Huey Wong,Naoyuki Taniguchi +14 more
TL;DR: Results indicate that 7-alkynyl-fucose is a highly sensitive and powerful tool for basic glycobiology research and clinical application for biomarker discovery.
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Silylene/Oxazolidinone Double-Locked Sialic Acid Building Blocks for Efficient Sialylation Reactions in Dichloromethane
TL;DR: In this paper, the authors describe efficient sialylation reactions in CH2Cl2 with the use of silylene/oxazolidinone double-locked sialic acid building blocks.
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Solution structures and behavior of trans-RuH(eta(1)-BH(4)) (binap)(1,2-diamine) complexes.
TL;DR: This inherent high acidity, coupled with the lability and chemical properties of the BH4 ligand, allows for precatalyst activation without the need for an added base, in contrast to trans‐RuCl2[(S)‐tolbinap](1,2‐diamine) precatalysts, which require a strong base for generation of a catalytic species.
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Parallel-stacked aromatic hosts for orienting small molecules in a magnetic field: induced residual dipolar coupling by encapsulation.
TL;DR: It is reported that columnar molecular hosts with parallel-aligned aromatics are magnetically oriented and exhibit observable RDC, and, upon encapsulation, an RDC silent guest is placed in alignment with the host and magnetic field and displays detectable induced RDC.