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Yu-Xin Li
Researcher at University of California, San Diego
Publications - 6
Citations - 709
Yu-Xin Li is an academic researcher from University of California, San Diego. The author has contributed to research in topics: Caenorhabditis elegans & Endosome. The author has an hindex of 5, co-authored 6 publications receiving 601 citations.
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Journal ArticleDOI
Identification of cross-linked peptides from complex samples
Bing Yang,Yan-Jie Wu,Ming Zhu,Sheng-Bo Fan,Jinzhong Lin,Kun Zhang,Shuang Li,Hao Chi,Yu-Xin Li,Hai-Feng Chen,Shukun Luo,Yue-He Ding,Le-Heng Wang,Zhiqi Hao,Li-Yun Xiu,She Chen,Keqiong Ye,Si-Min He,Meng-Qiu Dong +18 more
TL;DR: pLink as mentioned in this paper is a software for data analysis of cross-linked proteins coupled with mass-spectrometry analysis, which is compatible with multiple homo- or hetero-bifunctional cross-linkers.
Journal ArticleDOI
Mapping native disulfide bonds at a proteome scale
Shan Lu,Sheng-Bo Fan,Bing Yang,Yu-Xin Li,Jia-Ming Meng,Long Wu,Pin Li,Kun Zhang,Mei-Jun Zhang,Yan Fu,Jincai Luo,Rui-Xiang Sun,Si-Min He,Meng-Qiu Dong +13 more
TL;DR: Using pLink-SS, a high-throughput mass spectrometry method, all native disulfide bonds of a monoclonal antibody and ten standard proteins are mapped and many regulatory disulfides involving catalytic or metal-binding cysteine residues are discovered.
Journal ArticleDOI
Insulin signaling regulates longevity through protein phosphorylation in Caenorhabditis elegans
Wen-Jun Li,Chen Wei Wang,Chen Wei Wang,Li Tao,Yong Hong Yan,Mei Jun Zhang,Zexian Liu,Zexian Liu,Yu-Xin Li,Han Qing Zhao,Xue Mei Li,Xian Dong He,Yu Xue,Yu Xue,Meng-Qiu Dong +14 more
TL;DR: This study profiles IIS-dependent phosphorylation changes in a large-scale quantitative phosphoproteomic analysis of wild-type and three IIS mutant Caenorhabditis elegans strains and reveals detailed functional insights into longevity.
Journal ArticleDOI
Correction: Characterization of PUD-1 and PUD-2, Two Proteins Up-Regulated in a Long-Lived daf-2 Mutant
Yue-He Ding,Yun-Guang Du,Shukun Luo,Yu-Xin Li,Tie-Mei Li,Sawako Yoshina,Xing Wang,Karsten Klage,Shohei Mitani,Keqiong Ye,Meng-Qiu Dong +10 more
TL;DR: There is an error in the text for the hqEx130 allele, which appears in rows 33- 38 in Table S5.
Journal ArticleDOI
Serum- and Glucocorticoid-Inducible Kinase-1 (SGK-1) Plays a Role in Membrane Trafficking in Caenorhabditis elegans
TL;DR: The mammalian serum- and glucocorticoid-inducible kinase SGK1 regulates the endocytosis of ion channels and is proposed that SGK-1 function is required for lipid homeostasis and that it acts at different intracellular trafficking steps.